Acetaminophen for Kids' Vaccines Greensboro NC

Fever after a vaccination is a normal and essential part of building an immune response, and giving children acetaminophen -- best known in the U.S. as Tylenol -- after a shot could dampen that response, a new study finds. With some vaccines, transient fever means that a child's immune system is processing the immunization, providing them with the best protection, explained Dr. Robert T. Chen, a blood safety specialist at the U.S. Centers for Disease Control and Prevention.

Dr. James Anthony Pascale
(336) 832-6663
Greensboro, NC
Specialty
Pediatrics

Kilpatrick George R Jr Md PA
(336) 275-7658
601 East Market Street
Greensboro, NC
 
Altheimer Michael D MD
(336) 378-1074
1002 North Church Street Suite 400
Greensboro, NC
 
Guilford Medical Center P A
(336) 275-1306
104 West Northwood Street
Greensboro, NC
 
Lebauer Healthcare - Lebauer Internal Medicine
(336) 547-1792
1200 North Elm Street
Greensboro, NC
 
James Anthony Pascale, MD
(336) 832-6663
Greensboro, NC
Specialties
Pediatrics, Neonatal-Perinatal Medicine
Gender
Male
Education
Medical School: Bowman Gray Sch Of Med Of Wake Forest Univ, Winston-Salem Nc 27157
Graduation Year: 1972

Data Provided by:
Kritzer Randy O MD
(336) 378-1040
301 East Wendover Avenue Suite 211
Greensboro, NC
 
William D Clark
(336) 299-3183
510 N Elam Ave
Greensboro, NC
Specialty
Pediatrics

Data Provided by:
Steven Cochran Klein, MD
(336) 547-1751
520 N Elam Ave
Greensboro, NC
Specialties
Cardiology, Pediatrics
Gender
Male
Education
Medical School: Harvard Med Sch, Boston Ma 02115
Graduation Year: 1983

Data Provided by:
David Jeffrey Williams
(336) 832-6160
1200 N Elm St
Greensboro, NC
Specialty
Pediatrics, Pediatric Critical Care Medicine

Data Provided by:
Data Provided by:

Acetaminophen for Kids' Vaccines

Provided By:

THURSDAY, Oct. 15 (HealthDay News) -- Fever after a vaccination is a normal and essential part of building an immune response, and giving children acetaminophen -- best known in the U.S. as Tylenol -- after a shot could dampen that response, a new study finds.

With some vaccines, transient fever means that a child's immune system is processing the immunization, providing them with the best protection, explained Dr. Robert T. Chen, a blood safety specialist at the U.S. Centers for Disease Control and Prevention.

Therefore, "unless your doctor specifically recommends it, do not administer fever-reducing medicines at the same time as vaccination to prevent your child from developing a fever," said Chen, who wrote an editorial accompanying a report in the Oct. 17 issue of The Lancet.

"It is still okay to use antipyretics to treat a fever, but just not recommended to prevent fever," he added. "High fevers can be serious, especially in infants. It is important to work with your doctor to provide the best care for your child."

For the study, a research team led by Dr. Roman Prymula, from the University of Defence in Hradec Kralove, Czech Republic, did two studies, one when children received their first vaccination and another when they received their booster shot.

The vaccinations were routine for protection against pneumococcal disease, Haemophilus influenzae type b (Hib), diphtheria, tetanus, whooping cough, hepatitis B, polio and rotavirus.

The 459 infants in the studies were randomly assigned to get acetaminophen every six to eight hours for 24 hours after vaccination or no acetaminophen.

Prymula's team found that fewer infants who received acetaminophen had a fever, but these babies also had significantly fewer antibodies against pneumococcal disease, Haemophilus influenzae type b, diphtheria and tetanus toxoids, and for one of the whooping cough antibodies compared with infants who did not get acetaminophen.

They believe the pain reliever's anti-inflammatory activity might trigger "interference" to healthy immune system antibody responses, explaining the weakened immunization.

"Unless there are specific reasons for controlling fever, for example, in a child with history of febrile convulsions, Tylenol and other fever reducers should not be routinely given along with immunizations," Chen said.

Infectious disease expert Dr. Marc Siegel, an associate professor of medicine at New York University School of Medicine in New York City, said that "the conclusion that Tylenol not only suppresses fever, but also decreases immune response is plausible. After all, what is an immune response? It's an inflammatory response."

Siegel agrees that acetaminophen should not be routinely given to infants to prevent fever after vaccination. "But, if the kid is sick, treat the sickness. If the kid is very sick, I would get the fever down," he said.

And what about the vaccine for the H1N1 flu? According to Siegel, "giving an infant Tylenol before an H1N1 flu vaccine shot may not be a problem, because the immune response to the vaccine has been so robust."

More information

For more information on vaccines, visit the U.S. Centers for Disease Control and Prevention.

SOURCES: Robert T. Chen, M.D., blood safety specialist, U.S. Centers for Disease Control and Prevention, Atlanta; Marc Siegel, M.D., associate professor, medicine, New York University School of Medicine, New York City;Oct. 17, 2009, The Lancet

Author: By Steven Reinberg
HealthDay Reporter

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Read Article at HealthDay.com