Age-Related Cataracts Charlotte NC

The EphA2 gene encodes an enzyme that plays a role in the repair of damaged proteins in the eye. Expression of the EphA2 gene decreases with age, which means damaged proteins can clump together and cause the eye lens to become cloudy.

Thomas Kent Mundorf, MD
(704) 334-3222
1718 E 4th St Ste 703
Charlotte, NC
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Ophthalmology
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Medical School: Bowman Gray Sch Of Med Of Wake Forest Univ, Winston-Salem Nc 27157
Graduation Year: 1982

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John Edward Weaver, MD
(704) 372-7577
1600 E 3rd St
Charlotte, NC
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Medical School: Med Univ Of Sc Coll Of Med, Charleston Sc 29425
Graduation Year: 1978

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Brian R Kosobucki, MD
Charlotte, NC
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Medical School: Bowman Gray Sch Of Med Of Wake Forest Univ, Winston-Salem Nc 27157
Graduation Year: 1998

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Galen Grayson, MD
(704) 295-0001
817 E Morehead St Ste 200
Charlotte, NC
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Medical School: Harvard Med Sch, Boston Ma 02115
Graduation Year: 1988

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James Joseph Bedrick, MD
(704) 334-2020
2015 Randolph Rd Ste 108
Charlotte, NC
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Medical School: Univ Of Nc At Chapel Hill Sch Of Med, Chapel Hill Nc 27599
Graduation Year: 1977

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Donald Philip Renaldo, MD
(704) 376-5424
1718 E Fourth St Presbyterian Med Ctr Ste 908
Charlotte, NC
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Medical School: Temple Univ Sch Of Med, Philadelphia Pa 19140
Graduation Year: 1974

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Charles Adam Blotnick, MD
(704) 334-6175
2015 Randolph Rd Ste 108
Charlotte, NC
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Medical School: Univ Of Vt Coll Of Med, Burlington Vt 05405
Graduation Year: 1992

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Norman M Sawyer, MD
(704) 332-8144
2024 Randolph Rd Ste A
Charlotte, NC
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Medical School: George Washington Univ Sch Of Med & Hlth Sci, Washington Dc 20037
Graduation Year: 1960

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Curtis Coleman Reeves Jr, MD
1212 S Mint St
Charlotte, NC
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Medical School: Meharry Med Coll Sch Of Med, Nashville Tn 37208
Graduation Year: 1977

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Mac J Hough, MD
(704) 523-6529
4311 Darwin Cir
Charlotte, NC
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Medical School: Med Coll Virginia
Graduation Year: 1945

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Age-Related Cataracts

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FRIDAY, July 31 (HealthDay News) -- A gene associated with the formation of age-related cataract, a leading cause of blindness, has been identified by scientists.

The EphA2 gene encodes an enzyme that plays a role in the repair of damaged proteins in the eye. Expression of the EphA2 gene decreases with age, which means damaged proteins can clump together and cause the eye lens to become cloudy, resulting in obscured vision, according to the study in the July 31 issue of the journal PLoS Genetics.

The international group of researchers, including a team from Case Western Reserve University in Cleveland, have identified several mutations in the EphA2 gene that are associated with age-related cataract. They plan to search for more mutations.

Identifying the underlying causes of age-related cataract may help lead to new treatments and even ways to prevent the condition, the study authors noted.

By the time they're 80 years old, more than half of Americans will have a cataract or have had cataract surgery, according to a news release about the study.

More information

The U.S. National Eye Institute has more about cataract.

SOURCE: Case Western Reserve University, news release, July 30, 2009

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