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Age-Related Cataracts Durham NC

The EphA2 gene encodes an enzyme that plays a role in the repair of damaged proteins in the eye. Expression of the EphA2 gene decreases with age, which means damaged proteins can clump together and cause the eye lens to become cloudy.

John William Cline, MD
(336) 597-2826
1110 W Main St
Durham, NC
Specialties
Ophthalmology
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Male
Education
Medical School: Va Commonwealth Univ, Med Coll Of Va Sch Of Med, Richmond Va 23298
Graduation Year: 1958
Hospital
Hospital: Person Memorial Hospital, Roxboro, Nc; North Carolina Eye And Ear Hos, Durham, Nc
Group Practice: North Carolina Eye & Ear

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Lawrence White Moore Jr, MD
(919) 682-9341
1110 W Main St
Durham, NC
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Ophthalmology
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Male
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Spanish
Education
Medical School: Duke Univ Sch Of Med, Durham Nc 27710
Graduation Year: 1963
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Hospital: North Carolina Eye And Ear Hos, Durham, Nc
Group Practice: North Carolina Eye & Ear Hosp

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Sharon Fekrat, MD
(919) 681-0341
PO Box 3802 Erwin Road Duke Univ,
Durham, NC
Specialties
Ophthalmology
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Female
Education
Medical School: Univ Of Chicago, Pritzker Sch Of Med, Chicago Il 60637
Graduation Year: 1991

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Sanjay Girdhari Asrani, MD
(919) 684-8656
Erwin Road Box 3802,
Durham, NC
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Ophthalmology
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Male
Education
Medical School: Seth G S Med Coll, Univ Of Bombay, Bombay, Maharashtra, India
Graduation Year: 1988

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Claxton Allen Baer, MD
(404) 778-4530
2213 Elba Street,
Durham, NC
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Ophthalmology
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Medical School: Univ Of Va Sch Of Med, Charlottesville Va 22908
Graduation Year: 2000

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Cadmus Collins Rich, MD
(919) 682-9341
1110 W Main St
Durham, NC
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Ophthalmology
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Male
Education
Medical School: Univ Of Nc At Chapel Hill Sch Of Med, Chapel Hill Nc 27599
Graduation Year: 1995

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Joan Therese Roberts, MD
(919) 682-9341
1110 W Main St
Durham, NC
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Ophthalmology
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Female
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Medical School: Duke Univ Sch Of Med, Durham Nc 27710
Graduation Year: 1989

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Christine Elise Speer, MD
(919) 684-3771
Box 3802 Erwin Road,
Durham, NC
Specialties
Ophthalmology
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Female
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Medical School: Univ Of Ar Coll Of Med, Little Rock Ar 72205
Graduation Year: 1999

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Ellen E Anderson, MD
Durham, NC
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Ophthalmology
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Female
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Medical School: Univ Of Mn Med Sch-Minneapolis, Minneapolis Mn 55455
Graduation Year: 1992

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Prithvi Mruthyunjaya, MD
(919) 684-8434
Box 3802 Erwin Rd,
Durham, NC
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Ophthalmology
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Male
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Medical School: Albany Med Coll, Albany Ny 12208
Graduation Year: 1996

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Age-Related Cataracts

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FRIDAY, July 31 (HealthDay News) -- A gene associated with the formation of age-related cataract, a leading cause of blindness, has been identified by scientists.

The EphA2 gene encodes an enzyme that plays a role in the repair of damaged proteins in the eye. Expression of the EphA2 gene decreases with age, which means damaged proteins can clump together and cause the eye lens to become cloudy, resulting in obscured vision, according to the study in the July 31 issue of the journal PLoS Genetics.

The international group of researchers, including a team from Case Western Reserve University in Cleveland, have identified several mutations in the EphA2 gene that are associated with age-related cataract. They plan to search for more mutations.

Identifying the underlying causes of age-related cataract may help lead to new treatments and even ways to prevent the condition, the study authors noted.

By the time they're 80 years old, more than half of Americans will have a cataract or have had cataract surgery, according to a news release about the study.

More information

The U.S. National Eye Institute has more about cataract.

SOURCE: Case Western Reserve University, news release, July 30, 2009

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