Age-Related Cataracts Wilmington NC

The EphA2 gene encodes an enzyme that plays a role in the repair of damaged proteins in the eye. Expression of the EphA2 gene decreases with age, which means damaged proteins can clump together and cause the eye lens to become cloudy.

Kathleen Canning Leone, MD
(910) 763-3601
1729 New Hanover Medical Park Dr
Wilmington, NC
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Ophthalmology
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Medical School: Georgetown Univ Sch Of Med, Washington Dc 20007
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Hospital: New Hanover Reg Med Ctr, Wilmington, Nc
Group Practice: Eye Associates Of Wilmington; Eye Associates Of Wilmington Pa

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Susan Andracchi, MD
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1717 Shipyard Blvd Ste 140
Wilmington, NC
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Medical School: A Einstein Coll Of Med Of Yeshiva Univ, Bronx Ny 10461
Graduation Year: 1991

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Katherine Isabel Ochsner, MD
(409) 772-8102
1729 New Hanover Medical Park Dr
Wilmington, NC
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Medical School: La State Univ Sch Of Med In Shreveport, Shreveport La 71130
Graduation Year: 1987

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Igor Westra, MD
(910) 254-2023
1801 New Hanover Medical Park Dr
Wilmington, NC
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Medical School: Dartmouth Med, Hanover Nh 03755
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Stephen Lee Kash, MD
(910) 763-7316
1120 Med Ctr Dr
Wilmington, NC
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Medical School: Washington Univ Sch Of Med, St Louis Mo 63110
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Hospital: Cape Fear Mem Hosp, Wilmington, Nc
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Ernest Tilghman Poole, MD
(919) 392-6149
7400 Myrtle Grove Rd
Wilmington, NC
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Medical School: Duke Univ Sch Of Med, Durham Nc 27710
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Molly Virginia Allen, MD
(910) 763-7316
1120 Medical Center Dr
Wilmington, NC
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Medical School: Univ Of Tx Med Sch At San Antonio, San Antonio Tx 78284
Graduation Year: 1980
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Hospital: New Hanover Reg Med Ctr, Wilmington, Nc; Cape Fear Mem Hosp, Wilmington, Nc
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Timothy Gerald Kelly, MD
(910) 762-0057
1915 Tradd Ct
Wilmington, NC
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Medical School: Univ Of Al Sch Of Med, Birmingham Al 35294
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Richard D Hawkins, MD
(910) 763-3601
1915 Glen Meade Rd
Wilmington, NC
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Medical School: Duke Univ Sch Of Med, Durham Nc 27710
Graduation Year: 1997

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James L Kesler, MD
(910) 763-7316
1120 Med Ctr Dr
Wilmington, NC
Specialties
Ophthalmology
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Male
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Medical School: Washington Univ Sch Of Med, St Louis Mo 63110
Graduation Year: 1975
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Hospital: New Hanover Reg Med Ctr, Wilmington, Nc; Cape Fear Mem Hosp, Wilmington, Nc
Group Practice: Coastal Carolina Eye Clinic Pa

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Age-Related Cataracts

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FRIDAY, July 31 (HealthDay News) -- A gene associated with the formation of age-related cataract, a leading cause of blindness, has been identified by scientists.

The EphA2 gene encodes an enzyme that plays a role in the repair of damaged proteins in the eye. Expression of the EphA2 gene decreases with age, which means damaged proteins can clump together and cause the eye lens to become cloudy, resulting in obscured vision, according to the study in the July 31 issue of the journal PLoS Genetics.

The international group of researchers, including a team from Case Western Reserve University in Cleveland, have identified several mutations in the EphA2 gene that are associated with age-related cataract. They plan to search for more mutations.

Identifying the underlying causes of age-related cataract may help lead to new treatments and even ways to prevent the condition, the study authors noted.

By the time they're 80 years old, more than half of Americans will have a cataract or have had cataract surgery, according to a news release about the study.

More information

The U.S. National Eye Institute has more about cataract.

SOURCE: Case Western Reserve University, news release, July 30, 2009

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