Blood Flow Mismatch in Pancreatic Cancers Asheville NC

Finnish researchers say they have identified a blood-flow metabolism mismatch that predicts pancreatic cancer aggressiveness. The investigators used a three-dimensional imaging technique called positron emission tomography (PET) to measure blood flow and glucose consumption -- a measure of general metabolic activity of a tissue -- in 26 people.

Jeffrey S Roberts
(828) 253-7077
445 Biltmore Ave
Asheville, NC
Specialty
Radiation Oncology

Data Provided by:
Krystal S Bottom, MD
(828) 213-5770
445 Biltmore Ave Ste 101
Asheville, NC
Specialties
Oncology (Cancer)
Gender
Female
Education
Medical School: Univ Of Fl Coll Of Med, Gainesville Fl 32610
Graduation Year: 1989

Data Provided by:
Paul Langlie Martin, MD
(828) 254-2700
31 College Pl Ste B210
Asheville, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Washington Univ Sch Of Med, St Louis Mo 63110
Graduation Year: 1987

Data Provided by:
Christopher Haekang Chay
(828) 253-4262
445 Biltmore Ave
Asheville, NC
Specialty
Hematology / Oncology, Medical Oncology

Data Provided by:
Mridu S Chand
(828) 253-4262
445 Biltmore Ave
Asheville, NC
Specialty
Internal Medicine, Hematology / Oncology

Data Provided by:
Michael Joseph Messino, MD
(704) 253-7077
445 Biltmore Ave Ste G109
Asheville, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Oh State Univ Coll Of Med, Columbus Oh 43210
Graduation Year: 1979
Hospital
Hospital: Haywood Reg Med Ctr, Clyde, Nc; Spruce Pine Community Hospital, Spruce Pine, Nc; St Josephs Hospital, Asheville, Nc
Group Practice: Cancer Care

Data Provided by:
Ronald Myron Friedman
(828) 253-4262
445 Biltmore Ave
Asheville, NC
Specialty
Internal Medicine, Hematology / Oncology

Data Provided by:
Michael Joseph Messino
(828) 253-4262
445 Biltmore Ave
Asheville, NC
Specialty
Medical Oncology

Data Provided by:
Quinten C Black
(828) 253-7077
445 Biltmore Ave
Asheville, NC
Specialty
Radiation Oncology

Data Provided by:
Paul Michael Ahearne, MD
(828) 350-7515
131 McDowell St Ste 100
Asheville, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Duke Univ Sch Of Med, Durham Nc 27710
Graduation Year: 1988

Data Provided by:
Data Provided by:

Blood Flow Mismatch in Pancreatic Cancers

Provided By:

WEDNESDAY, Aug. 26 (HealthDay News) -- Finnish researchers say they have identified a blood-flow metabolism mismatch that predicts pancreatic cancer aggressiveness.

The investigators used a three-dimensional imaging technique called positron emission tomography (PET) to measure blood flow and glucose consumption -- a measure of general metabolic activity of a tissue -- in 26 people. The researchers noted that blood flow in malignant tumors was 60 percent less than in normal pancreatic tissue.

The findings may help explain why many pancreatic cancer patients have a poor response to radiation treatment and chemotherapy, the study authors noted in their report published Aug. 25 in Clinical Cancer Research.

"Imaging of several of these tumor parameters might be important for the planning and success of [cancer] therapies," study author Dr. Gaber Komar, research fellow at the Turku PET Center, said in a news release from the American Association for Cancer Research. "We believe that a better understanding of these mechanisms may help overcome the general treatment resistance of pancreatic cancer."

"This study confirms that blood flow metabolism mismatch exists in pancreatic tumors, similar to other cancers such as breast and lung cancers, and predicts poor patient outcome," Dr. David Mankoff, a professor of radiology, medicine and bioengineering at the University of Washington in Seattle, said in the news release.

"A blood flow metabolism mismatch by PET appears to be associated with cancer aggressiveness and treatment resistance. We've only recently recognized this pattern as a result of advantages in functional imaging methods," added Mankoff.

More information

The American Cancer Society has more about pancreatic cancer.

SOURCE: American Association for Cancer Research, news release, Aug. 25, 2009

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Read Article at HealthDay.com