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Blood Flow Mismatch in Pancreatic Cancers Boone NC

Finnish researchers say they have identified a blood-flow metabolism mismatch that predicts pancreatic cancer aggressiveness. The investigators used a three-dimensional imaging technique called positron emission tomography (PET) to measure blood flow and glucose consumption -- a measure of general metabolic activity of a tissue -- in 26 people.

Theodore Flint Gray III, MD
(828) 264-8004
870 State Farm Rd Ste 103B
Boone, NC
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Oncology (Cancer), Internal Medicine
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Medical School: Emory Univ Sch Of Med, Atlanta Ga 30322
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Dr.Yvonne Mack
(828) 262-4342
182 Virginia Street
Boone, NC
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Medical School: Bowman Gray Sch Of Med Of Wake Forest Univ
Year of Graduation: 1988
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Oncologist
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Dr.Michael Tate
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Lenoir, NC
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Theodore Gray
(828) 264-8004
Boone, NC
Specialty
Hematology-Oncology
Associated Hospitals
Po Box 3518

Charles H Pippitt Jr, MD
(336) 277-8800
1010 Bethesda Ct
Winston Salem, NC
Specialties
Oncology (Cancer), Gynecological Oncology, Obstetrics And Gynecology
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Male
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Medical School: Bowman Gray Sch Of Med Of Wake Forest Univ, Winston-Salem Nc 27157
Graduation Year: 1979
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Hospital: Forsyth Mem Hosp, Winston Salem, Nc; Medical Park Hospital, Winston Salem, Nc
Group Practice: Piedmont Hematology Oncology Associates

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Thomas Wendall Prewitt, MD
(828) 268-0688
838 State Farm Rd Ste 1
Boone, NC
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Medical School: Univ Of Ms Sch Of Med, Jackson Ms 39216
Graduation Year: 1988
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Hospital: Blowing Rock Hosp, Blowing Rock, Nc
Group Practice: Blue Ridge Surgical Group

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Walter Etchells Davis, MD
(828) 262-4332
330 Deerfield Rd
Boone, NC
Specialties
Oncology (Cancer)
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Male
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Medical School: Duke Univ Sch Of Med, Durham Nc 27710
Graduation Year: 1966

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Theodore Gray III
Watauga Medcl Ctr
Boone, NC
Associated Hospitals
Seby Jones Reg Cancer Ctr

Anastas C Provatas
(252) 744-2383
600 Moye Blvd
Greenville, NC
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Internal Medicine, Hematology / Oncology

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Dan German Blazer
(919) 684-8111
2100 Erwin Rd
Durham, NC
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Surgical Oncology

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Blood Flow Mismatch in Pancreatic Cancers

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WEDNESDAY, Aug. 26 (HealthDay News) -- Finnish researchers say they have identified a blood-flow metabolism mismatch that predicts pancreatic cancer aggressiveness.

The investigators used a three-dimensional imaging technique called positron emission tomography (PET) to measure blood flow and glucose consumption -- a measure of general metabolic activity of a tissue -- in 26 people. The researchers noted that blood flow in malignant tumors was 60 percent less than in normal pancreatic tissue.

The findings may help explain why many pancreatic cancer patients have a poor response to radiation treatment and chemotherapy, the study authors noted in their report published Aug. 25 in Clinical Cancer Research.

"Imaging of several of these tumor parameters might be important for the planning and success of [cancer] therapies," study author Dr. Gaber Komar, research fellow at the Turku PET Center, said in a news release from the American Association for Cancer Research. "We believe that a better understanding of these mechanisms may help overcome the general treatment resistance of pancreatic cancer."

"This study confirms that blood flow metabolism mismatch exists in pancreatic tumors, similar to other cancers such as breast and lung cancers, and predicts poor patient outcome," Dr. David Mankoff, a professor of radiology, medicine and bioengineering at the University of Washington in Seattle, said in the news release.

"A blood flow metabolism mismatch by PET appears to be associated with cancer aggressiveness and treatment resistance. We've only recently recognized this pattern as a result of advantages in functional imaging methods," added Mankoff.

More information

The American Cancer Society has more about pancreatic cancer.

SOURCE: American Association for Cancer Research, news release, Aug. 25, 2009

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