Breast Cancer Prognosis Asheville NC

Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments in Asheville.

Paul Michael Ahearne, MD
(828) 350-7515
131 McDowell St Ste 100
Asheville, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Duke Univ Sch Of Med, Durham Nc 27710
Graduation Year: 1988

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Wieslawa Pekal, MD
(828) 253-4262
445 Biltmore Ave # S-100
Asheville, NC
Specialties
Oncology (Cancer)
Gender
Female
Education
Medical School: Suny-Hlth Sci Ctr At Brooklyn, Coll Of Med, Brooklyn Ny 11203
Graduation Year: 1990
Hospital
Hospital: Haywood Reg Med Ctr, Clyde, Nc
Group Practice: Cancer Care Of Western North Carolina

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Wieslawa A Pekal
(828) 253-4262
445 Biltmore Ave
Asheville, NC
Specialty
Hematology / Oncology, Medical Oncology

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Don Vernon Jackson Jr, MD
(828) 254-8232
1 Doctors Dr
Asheville, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Univ Of Va Sch Of Med, Charlottesville Va 22908
Graduation Year: 1972

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Mridu S Chand
(828) 253-4262
445 Biltmore Ave
Asheville, NC
Specialty
Internal Medicine, Hematology / Oncology

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Ronald Myron Friedman
(828) 253-4262
445 Biltmore Ave
Asheville, NC
Specialty
Internal Medicine, Hematology / Oncology

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Barton Riley Paschal, MD
(828) 254-8232
1 Doctors Dr
Asheville, NC
Specialties
Oncology (Cancer), Hematology-Internal Medicine
Gender
Male
Education
Medical School: Emory Univ Sch Of Med, Atlanta Ga 30322
Graduation Year: 1976
Hospital
Hospital: Park Ridge Hospital, Fletcher, Nc; Mission St Joseph Health Syste, Asheville, Nc; St Josephs Hospital, Asheville, Nc
Group Practice: Asheville Hematology Oncology Assoc Pa; Asheville Hematology Oncology Associates Pa

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Krystal S Bottom, MD
(828) 213-5770
445 Biltmore Ave Ste 101
Asheville, NC
Specialties
Oncology (Cancer)
Gender
Female
Education
Medical School: Univ Of Fl Coll Of Med, Gainesville Fl 32610
Graduation Year: 1989

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Robert Carr Moffatt
(828) 258-2464
86 Victoria Rd
Asheville, NC
Specialty
Surgical Oncology

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Eric Ford Kuehn, MD
(828) 254-1111
90 Asheland Ave
Asheville, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Med Coll Of Ga Sch Of Med, Augusta Ga 30912
Graduation Year: 1990
Hospital
Hospital: Margaret R Pardee Memorial Hos, Hendersonvlle, Nc
Group Practice: Mountain Radiation Oncology Pa

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Breast Cancer Prognosis

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FRIDAY, May 22 (HealthDay News) -- Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments.

Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K. Witkiewicz, from Thomas Jefferson University in Philadelphia, and colleagues. The findings are published in the June issue of the American Journal of Pathology.

The second study, in the same issue of the journal, found that a similar lack of stromal caveolin-1 in mice was associated with more aggressive tumor growth in the rodents, according to Erica K. Sloan, from the Peter MacCallum Cancer Centre in East Melbourne, Australia, and colleagues.

The findings led Sloan's research team to hypothesize that caveolin-1 may work as a tumor suppressant, at least in stromal tissue.

"These studies suggest that stromal caveolin-1 expression may be a potential therapeutic target and a valuable prognostic indicator of breast cancer progression," Sloan and colleagues concluded in their report.

Previous research had found that caveolin-1 plays a big part in the development of breast cancer tumors, according to a news release from the journal.

More information

The American Cancer Society has more about breast cancer.

SOURCE: American Journal of Pathology, news release, May 22, 2009

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