Breast Cancer Prognosis Asheville NC

Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments in Asheville.

Quinten Curtis Black, MD
(828) 253-7077
445 Biltmore Ave Ste G102
Asheville, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Tulane Univ Sch Of Med, New Orleans La 70112
Graduation Year: 1998

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Michael Joseph Messino
(828) 253-4262
445 Biltmore Ave
Asheville, NC
Specialty
Medical Oncology

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Eric Ford Kuehn, MD
(828) 254-1111
90 Asheland Ave
Asheville, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Med Coll Of Ga Sch Of Med, Augusta Ga 30912
Graduation Year: 1990
Hospital
Hospital: Margaret R Pardee Memorial Hos, Hendersonvlle, Nc
Group Practice: Mountain Radiation Oncology Pa

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Christopher Haekang Chay
(828) 253-4262
445 Biltmore Ave
Asheville, NC
Specialty
Hematology / Oncology, Medical Oncology

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Mridu S Chand
(828) 253-4262
445 Biltmore Ave
Asheville, NC
Specialty
Internal Medicine, Hematology / Oncology

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Mohan Chand Thakuri
(828) 253-4262
445 Biltmore Ave
Asheville, NC
Specialty
Hematology / Oncology

Data Provided by:
Michael Joseph Messino, MD
(704) 253-7077
445 Biltmore Ave Ste G109
Asheville, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Oh State Univ Coll Of Med, Columbus Oh 43210
Graduation Year: 1979
Hospital
Hospital: Haywood Reg Med Ctr, Clyde, Nc; Spruce Pine Community Hospital, Spruce Pine, Nc; St Josephs Hospital, Asheville, Nc
Group Practice: Cancer Care

Data Provided by:
Shantae Ladon Lucas, MD
(828) 253-4262
445 Biltmore Ave Ste 100
Asheville, NC
Specialties
Oncology (Cancer)
Gender
Female
Education
Medical School: Univ Of Ky Coll Of Med, Lexington Ky 40536
Graduation Year: 1991

Data Provided by:
Paul Michael Ahearne, MD
(828) 350-7515
131 McDowell St Ste 100
Asheville, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Duke Univ Sch Of Med, Durham Nc 27710
Graduation Year: 1988

Data Provided by:
Shantae Ladon Lucas
(828) 253-4262
445 Biltmore Ave
Asheville, NC
Specialty
Hematology / Oncology, Medical Oncology

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Breast Cancer Prognosis

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FRIDAY, May 22 (HealthDay News) -- Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments.

Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K. Witkiewicz, from Thomas Jefferson University in Philadelphia, and colleagues. The findings are published in the June issue of the American Journal of Pathology.

The second study, in the same issue of the journal, found that a similar lack of stromal caveolin-1 in mice was associated with more aggressive tumor growth in the rodents, according to Erica K. Sloan, from the Peter MacCallum Cancer Centre in East Melbourne, Australia, and colleagues.

The findings led Sloan's research team to hypothesize that caveolin-1 may work as a tumor suppressant, at least in stromal tissue.

"These studies suggest that stromal caveolin-1 expression may be a potential therapeutic target and a valuable prognostic indicator of breast cancer progression," Sloan and colleagues concluded in their report.

Previous research had found that caveolin-1 plays a big part in the development of breast cancer tumors, according to a news release from the journal.

More information

The American Cancer Society has more about breast cancer.

SOURCE: American Journal of Pathology, news release, May 22, 2009

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