Breast Cancer Prognosis Asheville NC

Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments in Asheville.

Mridu S Chand
(828) 253-4262
445 Biltmore Ave
Asheville, NC
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Internal Medicine, Hematology / Oncology

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Barton Riley Paschal, MD
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Asheville, NC
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Oncology (Cancer), Hematology-Internal Medicine
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Medical School: Emory Univ Sch Of Med, Atlanta Ga 30322
Graduation Year: 1976
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Hospital: Park Ridge Hospital, Fletcher, Nc; Mission St Joseph Health Syste, Asheville, Nc; St Josephs Hospital, Asheville, Nc
Group Practice: Asheville Hematology Oncology Assoc Pa; Asheville Hematology Oncology Associates Pa

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Krystal Dawn Sanchez, MD
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Asheville, NC
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Medical School: Univ Of Fl Coll Of Med, Gainesville Fl 32610
Graduation Year: 1989

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Shantae Ladon Lucas
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445 Biltmore Ave
Asheville, NC
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Hematology / Oncology, Medical Oncology

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Wieslawa A Pekal
(828) 253-4262
445 Biltmore Ave
Asheville, NC
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Hematology / Oncology, Medical Oncology

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Orren Beaty III, DO
(828) 213-1740
50 Doctors Dr Ste 105
Asheville, NC
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Oncology (Cancer)
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Medical School: Kirksville Coll Of Osteo Med, Kirksville Mo 63501
Graduation Year: 1988

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Mohan Chand Thakuri
(828) 253-4262
445 Biltmore Ave
Asheville, NC
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Hematology / Oncology

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Michael Joseph Messino
(828) 253-4262
445 Biltmore Ave
Asheville, NC
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Medical Oncology

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Ronald Myron Friedman
(828) 253-4262
445 Biltmore Ave
Asheville, NC
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Internal Medicine, Hematology / Oncology

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Michael Joseph Messino, MD
(704) 253-7077
445 Biltmore Ave Ste G109
Asheville, NC
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Oncology (Cancer)
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Male
Education
Medical School: Oh State Univ Coll Of Med, Columbus Oh 43210
Graduation Year: 1979
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Hospital: Haywood Reg Med Ctr, Clyde, Nc; Spruce Pine Community Hospital, Spruce Pine, Nc; St Josephs Hospital, Asheville, Nc
Group Practice: Cancer Care

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Breast Cancer Prognosis

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FRIDAY, May 22 (HealthDay News) -- Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments.

Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K. Witkiewicz, from Thomas Jefferson University in Philadelphia, and colleagues. The findings are published in the June issue of the American Journal of Pathology.

The second study, in the same issue of the journal, found that a similar lack of stromal caveolin-1 in mice was associated with more aggressive tumor growth in the rodents, according to Erica K. Sloan, from the Peter MacCallum Cancer Centre in East Melbourne, Australia, and colleagues.

The findings led Sloan's research team to hypothesize that caveolin-1 may work as a tumor suppressant, at least in stromal tissue.

"These studies suggest that stromal caveolin-1 expression may be a potential therapeutic target and a valuable prognostic indicator of breast cancer progression," Sloan and colleagues concluded in their report.

Previous research had found that caveolin-1 plays a big part in the development of breast cancer tumors, according to a news release from the journal.

More information

The American Cancer Society has more about breast cancer.

SOURCE: American Journal of Pathology, news release, May 22, 2009

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