Breast Cancer Prognosis Camp Lejeune NC

Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments in Camp Lejeune.

Peter Michael Voorhees, MD
(919) 643-2791
1001 Scottsburg Trl
Hillsborough, NC
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Oncology (Cancer)
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Medical School: Univ Of Mi Med Sch, Ann Arbor Mi 48109
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John Brooks Cleek, MD
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14214 Ballantyne Lake Rd # 201
Charlotte, NC
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Internal Medicine, Medical Oncology
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Medical School: Med Coll Of Ga Sch Of Med, Augusta Ga 30912
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Hospital: Carolinas Med Ctr, Charlotte, Nc
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Gregory Michael Brouse
(704) 225-8966
1650 Faulk St
Monroe, NC
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Hematology / Oncology

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Krystal Dawn Sanchez, MD
50 Doctors Dr Ste 105
Asheville, NC
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Oncology (Cancer)
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Medical School: Univ Of Fl Coll Of Med, Gainesville Fl 32610
Graduation Year: 1989

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Louis F Diehl, MD
(919) 684-8964
Box 3872,
Durham, NC
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Oncology (Cancer)
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Medical School: Georgetown Univ Sch Of Med, Washington Dc 20007
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Donald Scott Murinson, MD
(704) 482-8936
1405 N Lafayette St Ste B
Shelby, NC
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Medical School: Univ Of Vt Coll Of Med, Burlington Vt 05405
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Hospital: Moses H Cone Memorial Hospital, Greensboro, Nc; Wesley Long Community Hospital, Greensboro, Nc
Group Practice: Regional Cancer Center Moses Cone Health System

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Rebecca F Connor, MD
(336) 716-4464
Medical Center Blvd,
Winston Salem, NC
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Oncology (Cancer)
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Male
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Graduation Year: 2007

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Gretchen G Kimmick, MD
(919) 668-0718
Ste 3800 Duke South Box 3204,
Durham, NC
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Medical School: Bowman Gray Sch Of Med Of Wake Forest Univ, Winston-Salem Nc 27157
Graduation Year: 1989

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Noel Anderson Brownlee, MD, PHD
(336) 806-0683
Medical Center Blvd,
Winston Salem, NC
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Graduation Year: 2007

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Arthur W Chaney
(704) 235-2580
170 Medical Park Rd
Mooresville, NC
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Breast Cancer Prognosis

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FRIDAY, May 22 (HealthDay News) -- Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments.

Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K. Witkiewicz, from Thomas Jefferson University in Philadelphia, and colleagues. The findings are published in the June issue of the American Journal of Pathology.

The second study, in the same issue of the journal, found that a similar lack of stromal caveolin-1 in mice was associated with more aggressive tumor growth in the rodents, according to Erica K. Sloan, from the Peter MacCallum Cancer Centre in East Melbourne, Australia, and colleagues.

The findings led Sloan's research team to hypothesize that caveolin-1 may work as a tumor suppressant, at least in stromal tissue.

"These studies suggest that stromal caveolin-1 expression may be a potential therapeutic target and a valuable prognostic indicator of breast cancer progression," Sloan and colleagues concluded in their report.

Previous research had found that caveolin-1 plays a big part in the development of breast cancer tumors, according to a news release from the journal.

More information

The American Cancer Society has more about breast cancer.

SOURCE: American Journal of Pathology, news release, May 22, 2009

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