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Breast Cancer Prognosis Cary NC

Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments in Cary.

Mark L Graham
(919) 233-8585
300 Ashville Ave
Cary, NC
Specialty
Hematology / Oncology, Medical Oncology

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Andrew Scott Kennedy, MD
(919) 854-4588
300 Ashville Ave Ste 110
Cary, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Loma Linda Univ Sch Of Med, Loma Linda Ca 92350
Graduation Year: 1991

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Mark L Graham II, MD
(919) 966-4431
Cary, NC
Specialties
Internal Medicine, Medical Oncology
Gender
Male
Education
Medical School: Mayo Med Sch, Rochester Mn 55905
Graduation Year: 1982
Hospital
Hospital: University Of North Carolina H, Chapel Hill, Nc
Group Practice: Cary Oncology

Data Provided by:
Mark L Graham, MD
(919) 233-8585
300 Ashville Ave Ste 180
Cary, NC
Specialties
Internal Medicine, Medical Oncology
Gender
Male
Education
Medical School: Mayo Med Sch, Rochester Mn 55905
Graduation Year: 1982

Data Provided by:
A Bartlett Pandite, MD
Cary, NC
Specialties
Oncology (Cancer)
Gender
Female
Education
Medical School: Univ Of Liverpool, Fac Of Med, Liverpool, Uk (352-06 Prior 1/71)
Graduation Year: 1983

Data Provided by:
Sunil J Desai, MD
(919) 233-0059
300 Keisler Dr Ste 204
Cary, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Municipal Med Coll, Gujarat Univ, Ahmedabad, Gujarat, India
Graduation Year: 1983

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Scott Lee Sailer, MD
(919) 854-4588
300 Ashville Ave Ste 110
Cary, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Harvard Med Sch, Boston Ma 02115
Graduation Year: 1984

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William R Berr, MR
(919) 852-1994
218 Ashville Ave Ste 20
Cary, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Graduation Year: 2007

Data Provided by:
Cassandra N Moore
(919) 854-6900
216 Ashville Ave
Cary, NC
Specialty
Hematology / Oncology

Data Provided by:
Kim M Boerick, MD
1001 Winstead Dr Ste 200
Cary, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Graduation Year: 2007

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Breast Cancer Prognosis

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FRIDAY, May 22 (HealthDay News) -- Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments.

Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K. Witkiewicz, from Thomas Jefferson University in Philadelphia, and colleagues. The findings are published in the June issue of the American Journal of Pathology.

The second study, in the same issue of the journal, found that a similar lack of stromal caveolin-1 in mice was associated with more aggressive tumor growth in the rodents, according to Erica K. Sloan, from the Peter MacCallum Cancer Centre in East Melbourne, Australia, and colleagues.

The findings led Sloan's research team to hypothesize that caveolin-1 may work as a tumor suppressant, at least in stromal tissue.

"These studies suggest that stromal caveolin-1 expression may be a potential therapeutic target and a valuable prognostic indicator of breast cancer progression," Sloan and colleagues concluded in their report.

Previous research had found that caveolin-1 plays a big part in the development of breast cancer tumors, according to a news release from the journal.

More information

The American Cancer Society has more about breast cancer.

SOURCE: American Journal of Pathology, news release, May 22, 2009

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