Breast Cancer Prognosis Charlotte NC

Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments in Charlotte.

Robert W Fraser III, MD
(704) 333-7376
200 Queens Rd
Charlotte, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Univ Of Pa Sch Of Med, Philadelphia Pa 19104
Graduation Year: 1975
Hospital
Hospital: Rowan Reg Med Ctr, Salisbury, Nc; Carolinas Med Ctr, Charlotte, Nc
Group Practice: Southeast Radiation Oncology Group Matthews Rad Oncology; Southeast Radiation Oncology Group Pa; Southeast Radiation Oncology Group Rock Hill Rad Oncology; Sou

Data Provided by:
Charles James Meakin III, MD
(704) 333-7376
200 Queens Rd Ste 400
Charlotte, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Univ Of Cincinnati Coll Of Med, Cincinnati Oh 45267
Graduation Year: 1985
Hospital
Hospital: Gaston Memorial Hospital, Gastonia, Nc
Group Practice: Southeast Radiation Oncology Group Matthews Rad Oncology; Southeast Radiation Oncology Group Pa; Southeast Radiation Oncology Group Rock Hill Rad Oncology; Southeast Radiation Oncology Gr

Data Provided by:
Mark Kirsch, MD
(704) 384-4189
PO Box 33549
Charlotte, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Univ Of The Witwatersrand, Med Sch, Johannesburg, So Africa
Graduation Year: 1969
Hospital
Hospital: Rowan Reg Med Ctr, Salisbury, Nc; Presbyterian Hospital, Charlotte, Nc
Group Practice: Southeast Radiation Oncology Group Matthews Rad Oncology; Southeast Radiation Oncology Group Pa; Southeast Radiation Oncology Group Rock Hill Rad Oncology;

Data Provided by:
Jonathan C Salo
(704) 355-2884
1025 Morehead Medical Dr
Charlotte, NC
Specialty
Surgical Oncology

Data Provided by:
John B Martinie
(704) 355-1813
1025 Morehead Medical Dr
Charlotte, NC
Specialty
Surgical Oncology

Data Provided by:
Jonathan Cyrus Salo, MD
(704) 355-3809
PO Box 32861
Charlotte, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Univ Of Ca, San Francisco, Sch Of Med, San Francisco Ca 94143
Graduation Year: 1985

Data Provided by:
Mark Mogul
(704) 384-1900
1712 E 4th St
Charlotte, NC
Specialty
Hematology / Oncology, Pediatric Hematology-Oncology

Data Provided by:
Timothy Earl Cloninger, MD
(704) 333-7376
200 Queens Rd
Charlotte, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Univ Of Nc At Chapel Hill Sch Of Med, Chapel Hill Nc 27599
Graduation Year: 1966
Hospital
Hospital: Rowan Reg Med Ctr, Salisbury, Nc; Carolinas Med Ctr, Charlotte, Nc
Group Practice: Southeast Radiation Oncology Group Matthews Rad Oncology; Southeast Radiation Oncology Group Pa; Southeast Radiation Oncology Group Rock Hill Rad Oncology; Sou

Data Provided by:
John Burnett Holt
(704) 384-4814
200 Hawthorne Lane
Charlotte, NC
Specialty
Hematology

Data Provided by:
William Karnes Poston
(704) 384-4814
200 Hawthorne Lane
Charlotte, NC
Specialty
Hematology

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Breast Cancer Prognosis

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FRIDAY, May 22 (HealthDay News) -- Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments.

Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K. Witkiewicz, from Thomas Jefferson University in Philadelphia, and colleagues. The findings are published in the June issue of the American Journal of Pathology.

The second study, in the same issue of the journal, found that a similar lack of stromal caveolin-1 in mice was associated with more aggressive tumor growth in the rodents, according to Erica K. Sloan, from the Peter MacCallum Cancer Centre in East Melbourne, Australia, and colleagues.

The findings led Sloan's research team to hypothesize that caveolin-1 may work as a tumor suppressant, at least in stromal tissue.

"These studies suggest that stromal caveolin-1 expression may be a potential therapeutic target and a valuable prognostic indicator of breast cancer progression," Sloan and colleagues concluded in their report.

Previous research had found that caveolin-1 plays a big part in the development of breast cancer tumors, according to a news release from the journal.

More information

The American Cancer Society has more about breast cancer.

SOURCE: American Journal of Pathology, news release, May 22, 2009

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