Breast Cancer Prognosis Charlotte NC

Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments in Charlotte.

John B Martinie
(704) 355-1813
1025 Morehead Medical Dr
Charlotte, NC
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Surgical Oncology

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John Burnett Holt
(704) 384-4814
200 Hawthorne Lane
Charlotte, NC
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Hematology

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Jonathan C Salo
(704) 355-2884
1025 Morehead Medical Dr
Charlotte, NC
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Surgical Oncology

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Mark Kirsch, MD
(704) 384-4189
PO Box 33549
Charlotte, NC
Specialties
Oncology (Cancer), Radiation Oncology
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Male
Education
Medical School: Univ Of The Witwatersrand, Med Sch, Johannesburg, So Africa
Graduation Year: 1969
Hospital
Hospital: Rowan Reg Med Ctr, Salisbury, Nc; Presbyterian Hospital, Charlotte, Nc
Group Practice: Southeast Radiation Oncology Group Matthews Rad Oncology; Southeast Radiation Oncology Group Pa; Southeast Radiation Oncology Group Rock Hill Rad Oncology;

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Herman Allen Godwin Jr, MD
(704) 841-1444
PO Box 32861
Charlotte, NC
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Oncology (Cancer)
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Male
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Medical School: Bowman Gray Sch Of Med Of Wake Forest Univ, Winston-Salem Nc 27157
Graduation Year: 1963

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Mark Mogul
(704) 384-1900
1712 E 4th St
Charlotte, NC
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Hematology / Oncology, Pediatric Hematology-Oncology

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Dr.Jayanthi Lea
(704) 355-2940
1025 Morehead Medical Dr # 600
Charlotte, NC
Gender
F
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Oncologist
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Hospital: Carolina Medical Center
Accepting New Patients: Yes
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1.0, out of 5 based on 1, reviews.

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James Bryan Hall, MD
(704) 355-8650
PO Box 32861
Charlotte, NC
Specialties
Oncology (Cancer), Gynecological Oncology
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Male
Education
Medical School: Med Univ Of Sc Coll Of Med, Charleston Sc 29425
Graduation Year: 1974

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Thomas Gary Trautmann, MD
(704) 333-7376
200 Queens Rd Ste 400
Charlotte, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Univ Of Cincinnati Coll Of Med, Cincinnati Oh 45267
Graduation Year: 1979
Hospital
Hospital: Rowan Reg Med Ctr, Salisbury, Nc; Carolinas Med Ctr, Charlotte, Nc; Presbyterian Hospital, Charlotte, Nc
Group Practice: Southeast Radiation Oncology Group Matthews Rad Oncology; Southeast Radiation Oncology Group Pa; Southeast Radiation Onco

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Wendy Graham Brick
(704) 302-8000
1025 Morehead Medical Dr
Charlotte, NC
Specialty
Hematology / Oncology

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Breast Cancer Prognosis

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FRIDAY, May 22 (HealthDay News) -- Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments.

Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K. Witkiewicz, from Thomas Jefferson University in Philadelphia, and colleagues. The findings are published in the June issue of the American Journal of Pathology.

The second study, in the same issue of the journal, found that a similar lack of stromal caveolin-1 in mice was associated with more aggressive tumor growth in the rodents, according to Erica K. Sloan, from the Peter MacCallum Cancer Centre in East Melbourne, Australia, and colleagues.

The findings led Sloan's research team to hypothesize that caveolin-1 may work as a tumor suppressant, at least in stromal tissue.

"These studies suggest that stromal caveolin-1 expression may be a potential therapeutic target and a valuable prognostic indicator of breast cancer progression," Sloan and colleagues concluded in their report.

Previous research had found that caveolin-1 plays a big part in the development of breast cancer tumors, according to a news release from the journal.

More information

The American Cancer Society has more about breast cancer.

SOURCE: American Journal of Pathology, news release, May 22, 2009

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