Breast Cancer Prognosis Concord NC

Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments in Concord.

Karis H Kremers, MD
(704) 783-1370
200 Medical Park Dr Ste 145
Concord, NC
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Oncology (Cancer)
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Female
Education
Medical School: Univ Of Ms Sch Of Med, Jackson Ms 39216
Graduation Year: 1980

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Christine Frances Piller
(704) 783-1542
920 Church St N
Concord, NC
Specialty
Hematology

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James G Wall
(704) 783-1370
100 Medical Park Dr
Concord, NC
Specialty
Internal Medicine, Hematology / Oncology

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John David Turner, MD
(704) 783-3369
200 Medical Park Dr Ste 145
Concord, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Emory Univ Sch Of Med, Atlanta Ga 30322
Graduation Year: 1992

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Ronald Dean Butler
(704) 593-0244
101 W. T. Harris Blvd
Charlote, NC
Specialty
Hematology / Oncology

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Thomas Albert Steffens, MD
(704) 783-1370
200 Medical Park Dr Ste 145
Concord, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Tufts Univ Sch Of Med, Boston Ma 02111
Graduation Year: 1982

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Richard F Williams, MD
(704) 783-3000
200 Medical Park Dr Ste 145
Concord, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Univ Of Ar Coll Of Med, Little Rock Ar 72205
Graduation Year: 1988

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James Hugh North
(704) 786-1108
200 Medical Park Dr
Concord, NC
Specialty
Surgical Oncology

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George Philip Sartiano, MD
Kannapolis, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: New York Univ Sch Of Med, New York Ny 10016
Graduation Year: 1960

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William Robert Mitchell, MD
(704) 593-0244
101 E Wt Harris Blvd Ste 5203
Charlotte, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Univ Of Louisville Sch Of Med, Louisville Ky 40202
Graduation Year: 1990
Hospital
Hospital: Union Mem Hosp, Monroe, Nc
Group Practice: Piedmont Oncology Specialist

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Breast Cancer Prognosis

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FRIDAY, May 22 (HealthDay News) -- Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments.

Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K. Witkiewicz, from Thomas Jefferson University in Philadelphia, and colleagues. The findings are published in the June issue of the American Journal of Pathology.

The second study, in the same issue of the journal, found that a similar lack of stromal caveolin-1 in mice was associated with more aggressive tumor growth in the rodents, according to Erica K. Sloan, from the Peter MacCallum Cancer Centre in East Melbourne, Australia, and colleagues.

The findings led Sloan's research team to hypothesize that caveolin-1 may work as a tumor suppressant, at least in stromal tissue.

"These studies suggest that stromal caveolin-1 expression may be a potential therapeutic target and a valuable prognostic indicator of breast cancer progression," Sloan and colleagues concluded in their report.

Previous research had found that caveolin-1 plays a big part in the development of breast cancer tumors, according to a news release from the journal.

More information

The American Cancer Society has more about breast cancer.

SOURCE: American Journal of Pathology, news release, May 22, 2009

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