Breast Cancer Prognosis Greensboro NC

Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments in Greensboro.

Matthew A Manning, MD
(336) 832-1100
501 N Elam Ave
Greensboro, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Va Commonwealth Univ, Med Coll Of Va Sch Of Med, Richmond Va 23298
Graduation Year: 1996

Data Provided by:
Adrian A Caracioni, MD
(336) 832-1100
501 N Elam Ave
Greensboro, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Inst De Med, Timisoara, Romania
Graduation Year: 1987

Data Provided by:
Gustav Charles Magrinat, MD
(336) 832-1100
501 N Elam Ave
Greensboro, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Univ Of Nc At Chapel Hill Sch Of Med, Chapel Hill Nc 27599
Graduation Year: 1987

Data Provided by:
John Emerson Feldmann, MD
(336) 832-0820
501 N Elam Ave
Greensboro, NC
Specialties
Oncology (Cancer), Hematology-Internal Medicine
Gender
Male
Education
Medical School: Cornell Univ Med Coll, New York Ny 10021
Graduation Year: 1968

Data Provided by:
Firas N Shadad
(336) 832-1100
501 N Elam Ave
Greensboro, NC
Specialty
Hematology / Oncology

Data Provided by:
Lauretta Ifeoma Odogwu
(336) 832-1100
501 N Elam Ave
Greensboro, NC
Specialty
Internal Medicine, Medical Oncology

Data Provided by:
Gary Bradley Sherrill
(336) 832-1100
501 N Elam Ave
Greensboro, NC
Specialty
Internal Medicine, Hematology / Oncology

Data Provided by:
Justin Ja-Li Wu, MD
(336) 832-1100
501 N Elam Ave
Greensboro, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Duke Univ Sch Of Med, Durham Nc 27710
Graduation Year: 1990

Data Provided by:
Mohamed Kamel Mohamed
(336) 832-1100
501 N Elam Ave
Greensboro, NC
Specialty
Internal Medicine, Medical Oncology

Data Provided by:
Nigel Thomas Goodchild, MD
(336) 832-1100
501 N Elam Ave
Greensboro, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Univ London, St Bartholomew'S Hosp Med Coll, (See 917-31)
Graduation Year: 1969

Data Provided by:
Data Provided by:

Breast Cancer Prognosis

Provided By:

FRIDAY, May 22 (HealthDay News) -- Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments.

Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K. Witkiewicz, from Thomas Jefferson University in Philadelphia, and colleagues. The findings are published in the June issue of the American Journal of Pathology.

The second study, in the same issue of the journal, found that a similar lack of stromal caveolin-1 in mice was associated with more aggressive tumor growth in the rodents, according to Erica K. Sloan, from the Peter MacCallum Cancer Centre in East Melbourne, Australia, and colleagues.

The findings led Sloan's research team to hypothesize that caveolin-1 may work as a tumor suppressant, at least in stromal tissue.

"These studies suggest that stromal caveolin-1 expression may be a potential therapeutic target and a valuable prognostic indicator of breast cancer progression," Sloan and colleagues concluded in their report.

Previous research had found that caveolin-1 plays a big part in the development of breast cancer tumors, according to a news release from the journal.

More information

The American Cancer Society has more about breast cancer.

SOURCE: American Journal of Pathology, news release, May 22, 2009

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Read Article at HealthDay.com