Breast Cancer Prognosis Greenville NC

Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments in Greenville.

Howard David Homesley, MD
(252) 744-3587
Leo Jenkins Cancer Ctr
Greenville, NC
Specialties
Oncology (Cancer), Gynecological Oncology
Gender
Male
Education
Medical School: Univ Of Nc At Chapel Hill Sch Of Med, Chapel Hill Nc 27599
Graduation Year: 1967

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Lillian P Burke, MD
(252) 744-2560
3E 127 Brody Med Sci Bldg
Greenville, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Graduation Year: 2007

Data Provided by:
Spencer O Raa, MR
(919) 551-2554
3E-106 Brody Bldg
Greenville, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Graduation Year: 2007

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Susan Gustke, MD
(252) 744-1000
202 W Berkshire Rd
Greenville, NC
Specialties
Internal Medicine, Hematology-Oncology
Gender
Female
Education
Medical School: Wv Univ Sch Of Med, Morgantown Wv 26506
Graduation Year: 1964
Hospital
Hospital: Pitt County Memorial Hospital, Greenville, Nc
Group Practice: Ecu Physicians Brody School Of Medicine

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Heather S Ambrose, MD
(252) 752-4610
1850 W Arlington Blvd
Greenville, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Graduation Year: 2007

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Ulf Lennart Karlsson, MD
(800) 782-8581
Greenville, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Karolinska Inst, Med Fak, Stockholm, Sweden
Graduation Year: 1968

Data Provided by:
James Ronald W Humbert, MD
(252) 816-4676
288 W Teaching Annex
Greenville, NC
Specialties
Oncology (Cancer), Pediatrics
Gender
Male
Education
Medical School: Centre Med Univ, Fac De Med, Geneve, Switzerland (Univ De Geneve)
Graduation Year: 1964

Data Provided by:
Gary Richard Jones, MD
(503) 494-1543
3282 Charles Blvd
Greenville, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Or Hlth Sci Univ Sch Of Med, Portland Or 97201
Graduation Year: 1980

Data Provided by:
Radhika Shah, MD
(252) 744-2560
Hem Onc Brody 3E 127 600 Moye Blvd
Greenville, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Graduation Year: 2007

Data Provided by:
Alex V Hnatov
(252) 329-0025
801 Wh Smith Blvd
Greenville, NC
Specialty
Radiation Oncology

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Breast Cancer Prognosis

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FRIDAY, May 22 (HealthDay News) -- Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments.

Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K. Witkiewicz, from Thomas Jefferson University in Philadelphia, and colleagues. The findings are published in the June issue of the American Journal of Pathology.

The second study, in the same issue of the journal, found that a similar lack of stromal caveolin-1 in mice was associated with more aggressive tumor growth in the rodents, according to Erica K. Sloan, from the Peter MacCallum Cancer Centre in East Melbourne, Australia, and colleagues.

The findings led Sloan's research team to hypothesize that caveolin-1 may work as a tumor suppressant, at least in stromal tissue.

"These studies suggest that stromal caveolin-1 expression may be a potential therapeutic target and a valuable prognostic indicator of breast cancer progression," Sloan and colleagues concluded in their report.

Previous research had found that caveolin-1 plays a big part in the development of breast cancer tumors, according to a news release from the journal.

More information

The American Cancer Society has more about breast cancer.

SOURCE: American Journal of Pathology, news release, May 22, 2009

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