Breast Cancer Prognosis Hickory NC

Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments in Hickory.

Michael Noah Tate, MD
(828) 324-9550
PO Box 3710
Hickory, NC
Specialties
Oncology (Cancer), Internal Medicine
Gender
Male
Education
Medical School: Univ Of Nc At Chapel Hill Sch Of Med, Chapel Hill Nc 27599
Graduation Year: 1982
Hospital
Hospital: Catawba Mem Hosp, Hickory, Nc
Group Practice: Northwestern Carolina Oncology & Hematology

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Terry Sarantou
(828) 327-9178
415 N Center St
Hickory, NC
Specialty
General Surgery, Surgical Oncology

Data Provided by:
John Oscar Del Charco, MD
(828) 326-3856
810 Fairgrove Church Rd
Hickory, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Univ Of South Fl Coll Of Med, Tampa Fl 33612
Graduation Year: 1993

Data Provided by:
Shannon K Tomlinson, MD
810 Fairgrove Church Rd
Hickory, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Female
Education
Medical School: Med Coll Of Ohio, Toledo Oh 43699
Graduation Year: 1998

Data Provided by:
Emmett Royce White, MD
PO Box 700
Valdese, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Bowman Gray Sch Of Med Of Wake Forest Univ, Winston-Salem Nc 27157
Graduation Year: 1954

Data Provided by:
Richard Orlowski, MD
(828) 324-9550
PO Box 3710
Hickory, NC
Specialties
Oncology (Cancer), Hematology-Internal Medicine
Gender
Male
Education
Medical School: Washington Univ Sch Of Med, St Louis Mo 63110
Graduation Year: 1978
Hospital
Hospital: Catawba Mem Hosp, Hickory, Nc; Frye Reg Med Ctr, Hickory, Nc
Group Practice: Northwestern Carolina Oncology & Hematology

Data Provided by:
Piyapong Vongkovit, MD
(828) 324-9550
Hickory, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Mahidol Univ-Ramathibodi Hosp, Fac Of Med, Bangkok, Thailand
Graduation Year: 1987

Data Provided by:
Piyapong Vongkovit, MD
(828) 324-9550
225 18th St SE
Hickory, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Mahidol Univ-Ramathibodi Hosp, Fac Of Med, Bangkok, Thailand
Graduation Year: 1987

Data Provided by:
William Reginald Sigmon, MD
(828) 326-3856
810 Fairgrove Church Rd
Hickory, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Univ Of Nc At Chapel Hill Sch Of Med, Chapel Hill Nc 27599
Graduation Year: 1987

Data Provided by:
Christopher R McDonald, MD
(828) 879-7536
PO Box 700
Valdese, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: La State Univ Sch Of Med In New Orleans, New Orleans La 70112
Graduation Year: 1972

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Breast Cancer Prognosis

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FRIDAY, May 22 (HealthDay News) -- Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments.

Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K. Witkiewicz, from Thomas Jefferson University in Philadelphia, and colleagues. The findings are published in the June issue of the American Journal of Pathology.

The second study, in the same issue of the journal, found that a similar lack of stromal caveolin-1 in mice was associated with more aggressive tumor growth in the rodents, according to Erica K. Sloan, from the Peter MacCallum Cancer Centre in East Melbourne, Australia, and colleagues.

The findings led Sloan's research team to hypothesize that caveolin-1 may work as a tumor suppressant, at least in stromal tissue.

"These studies suggest that stromal caveolin-1 expression may be a potential therapeutic target and a valuable prognostic indicator of breast cancer progression," Sloan and colleagues concluded in their report.

Previous research had found that caveolin-1 plays a big part in the development of breast cancer tumors, according to a news release from the journal.

More information

The American Cancer Society has more about breast cancer.

SOURCE: American Journal of Pathology, news release, May 22, 2009

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