Breast Cancer Prognosis High Point NC

Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments in High Point.

James F Plowden
(336) 802-2500
302 Westwood Ave
High Point, NC
Specialty
Hematology / Oncology, Medical Oncology

Data Provided by:
Bernard Ravi Chinnasami, MD
(336) 802-2500
302 Westwood Ave
High Point, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Madras Med Coll, Dr M G R Med Univ, Madras, Tn, India
Graduation Year: 1988

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Vallathucherry Chakalakumbil Harish
(336) 802-2500
302 Westwood Ave
High Point, NC
Specialty
Hematology / Oncology

Data Provided by:
James Francis Plowden, MD
(336) 802-2500
302 Westwood Ave
High Point, NC
Specialties
Oncology (Cancer), Internal Medicine
Gender
Male
Education
Medical School: Med Univ Of Sc Coll Of Med, Charleston Sc 29425
Graduation Year: 1973
Hospital
Hospital: High Point Regional Hospital, High Point, Nc
Group Practice: Cornerstone Health Care Emerywood

Data Provided by:
Mohamed Kamel Mohamed
(336) 832-1100
501 N Elam Ave
Greensboro, NC
Specialty
Internal Medicine, Medical Oncology

Data Provided by:
Susan Kidwell Williford, MD
(336) 802-2500
302 Westwood Ave
High Point, NC
Specialties
Oncology (Cancer)
Gender
Female
Education
Medical School: Bowman Gray Sch Of Med Of Wake Forest Univ, Winston-Salem Nc 27157
Graduation Year: 1984

Data Provided by:
George Herbert S Sanders, MD
(336) 802-2500
302 Westwood Ave
High Point, NC
Specialties
Oncology (Cancer), Internal Medicine
Gender
Male
Education
Medical School: Univ Of Nc At Chapel Hill Sch Of Med, Chapel Hill Nc 27599
Graduation Year: 1988

Data Provided by:
Bart Alan Frizzell, MD
(336) 878-6036
601 N Elm St
High Point, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Male
Education
Medical School: Univ Of Tn, Memphis, Coll Of Med, Memphis Tn 38163
Graduation Year: 1996

Data Provided by:
John Emerson Feldmann, MD
(336) 832-0820
501 N Elam Ave
Greensboro, NC
Specialties
Oncology (Cancer), Hematology-Internal Medicine
Gender
Male
Education
Medical School: Cornell Univ Med Coll, New York Ny 10021
Graduation Year: 1968

Data Provided by:
Lennis Pearcy Livesay, MD
(336) 832-1100
501 N Elam Ave
Greensboro, NC
Specialties
Oncology (Cancer)
Gender
Female
Education
Medical School: Univ Of Sc Sch Of Med, Columbia Sc 29208
Graduation Year: 1985

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Breast Cancer Prognosis

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FRIDAY, May 22 (HealthDay News) -- Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments.

Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K. Witkiewicz, from Thomas Jefferson University in Philadelphia, and colleagues. The findings are published in the June issue of the American Journal of Pathology.

The second study, in the same issue of the journal, found that a similar lack of stromal caveolin-1 in mice was associated with more aggressive tumor growth in the rodents, according to Erica K. Sloan, from the Peter MacCallum Cancer Centre in East Melbourne, Australia, and colleagues.

The findings led Sloan's research team to hypothesize that caveolin-1 may work as a tumor suppressant, at least in stromal tissue.

"These studies suggest that stromal caveolin-1 expression may be a potential therapeutic target and a valuable prognostic indicator of breast cancer progression," Sloan and colleagues concluded in their report.

Previous research had found that caveolin-1 plays a big part in the development of breast cancer tumors, according to a news release from the journal.

More information

The American Cancer Society has more about breast cancer.

SOURCE: American Journal of Pathology, news release, May 22, 2009

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