Breast Cancer Prognosis Jacksonville NC

Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments in Jacksonville.

Gerard M McPhee
(252) 633-1010
137 Medical Lane
Pollocksville, NC
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Radiation Oncology

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Bonnie Jeanne Goodwin, MD
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PO Box 68
Pollocksville, NC
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Russell Earle Burgess, MD
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PO Box 68
Pollocksville, NC
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Medical School: Bowman Gray Sch Of Med Of Wake Forest Univ, Winston-Salem Nc 27157
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Hospital: Onslow Memorial Hospital, Jacksonville, Nc
Group Practice: Ecu Physicians Brody School Of Medicine

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Mitchell Steven Anscher, MD
(919) 668-5637
PO Box 3085,
Durham, NC
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Medical School: Va Commonwealth Univ, Med Coll Of Va Sch Of Med, Richmond Va 23298
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Gina Vaccaro
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3404 Wake Forest Rd Ste 202
Raleigh, NC
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Hematology / Oncology

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Russell E Burgess
(252) 633-1010
137 Medical Lane
Pollocksville, NC
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Hematology / Oncology, Medical Oncology

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Bonnie J Goodwin
(252) 633-1010
137 Medical Lane
Pollocksville, NC
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Internal Medicine, Hematology / Oncology

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Bonnie Goodwin
(252) 633-1010
PO Box 68
Pollocksville, NC
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Medical Oncology
Associated Hospitals
Eastern Carolina Internal Medicine Pa

James Anthony Palermo, MD
(336) 527-7577
Medical Center Blvd,
Winston Salem, NC
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Oncology (Cancer), Radiation Oncology
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Male
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Medical School: Univ Of Nc At Chapel Hill Sch Of Med, Chapel Hill Nc 27599
Graduation Year: 1997

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Heather H Shearer
(336) 277-8800
1010 Bethesda Ct
Winston Salem, NC
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Breast Cancer Prognosis

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FRIDAY, May 22 (HealthDay News) -- Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments.

Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K. Witkiewicz, from Thomas Jefferson University in Philadelphia, and colleagues. The findings are published in the June issue of the American Journal of Pathology.

The second study, in the same issue of the journal, found that a similar lack of stromal caveolin-1 in mice was associated with more aggressive tumor growth in the rodents, according to Erica K. Sloan, from the Peter MacCallum Cancer Centre in East Melbourne, Australia, and colleagues.

The findings led Sloan's research team to hypothesize that caveolin-1 may work as a tumor suppressant, at least in stromal tissue.

"These studies suggest that stromal caveolin-1 expression may be a potential therapeutic target and a valuable prognostic indicator of breast cancer progression," Sloan and colleagues concluded in their report.

Previous research had found that caveolin-1 plays a big part in the development of breast cancer tumors, according to a news release from the journal.

More information

The American Cancer Society has more about breast cancer.

SOURCE: American Journal of Pathology, news release, May 22, 2009

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