Breast Cancer Prognosis Mooresville NC

Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments in Mooresville.

David Anthony Eagle, MD
(704) 799-3946
156 Centre Church Rd Ste 207
Mooresville, NC
Specialties
Oncology (Cancer)
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Male
Education
Medical School: Univ Of Va Sch Of Med, Charlottesville Va 22908
Graduation Year: 1993
Hospital
Hospital: St Francis Hosp & Med Ctr, Topeka, Ks; Carolinas Med Ctr, Charlotte, Nc

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Stephanie Lott Elkins, MD
(704) 894-0854
17006 Piermont St
Davidson, NC
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Internal Medicine, Medical Oncology
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Female
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Medical School: Univ Of Ms Sch Of Med, Jackson Ms 39216
Graduation Year: 1987

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John Dwyer Powderly
(704) 947-6599
9801 Kincey Ave
Huntersville, NC
Specialty
Hematology / Oncology

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Gayla Sue Lowery, MD
(704) 878-8789
PO Box 6297
Statesville, NC
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Oncology (Cancer), Radiation Oncology
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Female
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Medical School: Bowman Gray Sch Of Med Of Wake Forest Univ, Winston-Salem Nc 27157
Graduation Year: 1978

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James Hugh North
(704) 786-1108
200 Medical Park Dr
Concord, NC
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Surgical Oncology

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Arthur W Chaney
(704) 235-2580
170 Medical Park Rd
Mooresville, NC
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Radiation Oncology

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Vetta Higgs
(704) 367-6610
16455 Statesville Rd
Huntersville, NC
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Hematology / Oncology

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George Philip Sartiano, MD
Kannapolis, NC
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Oncology (Cancer)
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Male
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Medical School: New York Univ Sch Of Med, New York Ny 10016
Graduation Year: 1960

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Richard F Williams, MD
(704) 783-3000
200 Medical Park Dr Ste 145
Concord, NC
Specialties
Oncology (Cancer)
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Male
Education
Medical School: Univ Of Ar Coll Of Med, Little Rock Ar 72205
Graduation Year: 1988

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Thomas Albert Steffens, MD
(704) 783-1370
200 Medical Park Dr Ste 145
Concord, NC
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Oncology (Cancer)
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Male
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Medical School: Tufts Univ Sch Of Med, Boston Ma 02111
Graduation Year: 1982

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Breast Cancer Prognosis

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FRIDAY, May 22 (HealthDay News) -- Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments.

Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K. Witkiewicz, from Thomas Jefferson University in Philadelphia, and colleagues. The findings are published in the June issue of the American Journal of Pathology.

The second study, in the same issue of the journal, found that a similar lack of stromal caveolin-1 in mice was associated with more aggressive tumor growth in the rodents, according to Erica K. Sloan, from the Peter MacCallum Cancer Centre in East Melbourne, Australia, and colleagues.

The findings led Sloan's research team to hypothesize that caveolin-1 may work as a tumor suppressant, at least in stromal tissue.

"These studies suggest that stromal caveolin-1 expression may be a potential therapeutic target and a valuable prognostic indicator of breast cancer progression," Sloan and colleagues concluded in their report.

Previous research had found that caveolin-1 plays a big part in the development of breast cancer tumors, according to a news release from the journal.

More information

The American Cancer Society has more about breast cancer.

SOURCE: American Journal of Pathology, news release, May 22, 2009

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