Breast Cancer Prognosis Wilmington NC

Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments in Wilmington.

Arvil D Stephen, MD
(910) 772-7573
3151 S 17th St
Wilmington, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Graduation Year: 2007

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Andrew Philip Brown, MD
(910) 763-1137
2800 Ashton Dr
Wilmington, NC
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Oncology (Cancer), Radiation Oncology
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Male
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Medical School: Univ Of London, Royal Free Hosp Sch Med (See 917-34)
Graduation Year: 1978

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Peter C Mancusi-Ungaro
(910) 343-7597
2131 S 17th St
Wilmington, NC
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Hematology / Oncology

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Elizabeth Harrer Yoffe, MD
7221 Gray Gables
Wilmington, NC
Specialties
Oncology (Cancer)
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Female
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Medical School: Univ Of Fl Coll Of Med, Gainesville Fl 32610
Graduation Year: 1977

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John William Anagnost, MD
(910) 343-0447
1515 Doctors Cir
Wilmington, NC
Specialties
Oncology (Cancer), Hematology-Internal Medicine
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Male
Education
Medical School: Jefferson Med Coll-Thos Jefferson Univ, Philadelphia Pa 19107
Graduation Year: 1978
Hospital
Hospital: New Hanover Reg Med Ctr, Wilmington, Nc; Cape Fear Mem Hosp, Wilmington, Nc
Group Practice: Hanover Medical Specialists

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Peter Ungaro, MD
(910) 342-3001
109 Darley Ln
Wilmington, NC
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Oncology (Cancer)
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Male
Education
Graduation Year: 2007

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Brenda Ann Carroll, MD
(919) 341-3300
1202 Medical Center Dr
Cape Fear, NC
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Oncology (Cancer)
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Female
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Medical School: Med Univ Of Sc Coll Of Med, Charleston Sc 29425
Graduation Year: 1989

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Birgit Arb, MD
(919) 763-5182
1515 Doctors Cir
Wilmington, NC
Specialties
Oncology (Cancer)
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Female
Education
Medical School: Pa State Univ Coll Of Med, Hershey Pa 17033
Graduation Year: 1991

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Kenneth Irvin Fink
(910) 772-9202
2131 S 17th St
Wilmington, NC
Specialty
Medical Oncology

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William Mc Nulty, MD
(910) 763-5182
1515 Doctors Cir
Wilmington, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Univ Of Sc Sch Of Med, Columbia Sc 29208
Graduation Year: 1982

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Breast Cancer Prognosis

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FRIDAY, May 22 (HealthDay News) -- Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments.

Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K. Witkiewicz, from Thomas Jefferson University in Philadelphia, and colleagues. The findings are published in the June issue of the American Journal of Pathology.

The second study, in the same issue of the journal, found that a similar lack of stromal caveolin-1 in mice was associated with more aggressive tumor growth in the rodents, according to Erica K. Sloan, from the Peter MacCallum Cancer Centre in East Melbourne, Australia, and colleagues.

The findings led Sloan's research team to hypothesize that caveolin-1 may work as a tumor suppressant, at least in stromal tissue.

"These studies suggest that stromal caveolin-1 expression may be a potential therapeutic target and a valuable prognostic indicator of breast cancer progression," Sloan and colleagues concluded in their report.

Previous research had found that caveolin-1 plays a big part in the development of breast cancer tumors, according to a news release from the journal.

More information

The American Cancer Society has more about breast cancer.

SOURCE: American Journal of Pathology, news release, May 22, 2009

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