Breast Cancer Prognosis Winston Salem NC

Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments in Winston Salem.

Samer Ernest Bibawi, MD
(336) 277-8800
1010 Bethesda Ct
Winston Salem, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Univ Of Cairo, Fac Of Med, Cairo, Egypt (330-02 Prior 1/71)
Graduation Year: 1988

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Arthur William Blackstock
(336) 716-2255
Medical Center Blvd
Winston Salem, NC
Specialty
Radiation Oncology

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Richard A Brodkin
(336) 277-8800
1010 Bethesda Ct
Winston Salem, NC
Specialty
Hematology / Oncology

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Patricia Joan Zekan, MD
(336) 748-8626
359 Buckingham Rd
Winston Salem, NC
Specialties
Internal Medicine, Medical Oncology
Gender
Female
Education
Medical School: Wv Univ Sch Of Med, Morgantown Wv 26506
Graduation Year: 1978

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Christopher Reid Thomas
(336) 277-8800
1010 Bethesda Ct
Winston Salem, NC
Specialty
Internal Medicine, Hematology / Oncology

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Lisa Smith Evans, MD
(336) 718-5095
3333 Silas Creek Pkwy
Winston Salem, NC
Specialties
Oncology (Cancer), Radiation Oncology
Gender
Female
Education
Medical School: Univ Of South Fl Coll Of Med, Tampa Fl 33612
Graduation Year: 1984
Hospital
Hospital: Forsyth Mem Hosp, Winston Salem, Nc
Group Practice: Forsyth Regional Cancer Ctr

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Edward Gus Shaw
(336) 716-2255
Medical Center Blvd
Winston Salem, NC
Specialty
Radiation Oncology

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Perry Shen
(336) 716-2255
Medical Center Blvd
Winston Salem, NC
Specialty
General Surgery, Surgical Oncology

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Richard Alan Brodkin, MD
(336) 277-8800
1010 Bethesda Ct
Winston Salem, NC
Specialties
Oncology (Cancer), Hematology-Internal Medicine
Gender
Male
Education
Medical School: Bowman Gray Sch Of Med Of Wake Forest Univ, Winston-Salem Nc 27157
Graduation Year: 1974
Hospital
Hospital: Forsyth Mem Hosp, Winston Salem, Nc
Group Practice: Piedmont Hematology Oncology Associates

Data Provided by:
Judith Owen Hopkins, MD
(336) 277-8800
1010 Bethesda Ct
Winston Salem, NC
Specialties
Oncology (Cancer)
Gender
Female
Education
Medical School: Univ Of Va Sch Of Med, Charlottesville Va 22908
Graduation Year: 1977

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Breast Cancer Prognosis

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FRIDAY, May 22 (HealthDay News) -- Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments.

Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K. Witkiewicz, from Thomas Jefferson University in Philadelphia, and colleagues. The findings are published in the June issue of the American Journal of Pathology.

The second study, in the same issue of the journal, found that a similar lack of stromal caveolin-1 in mice was associated with more aggressive tumor growth in the rodents, according to Erica K. Sloan, from the Peter MacCallum Cancer Centre in East Melbourne, Australia, and colleagues.

The findings led Sloan's research team to hypothesize that caveolin-1 may work as a tumor suppressant, at least in stromal tissue.

"These studies suggest that stromal caveolin-1 expression may be a potential therapeutic target and a valuable prognostic indicator of breast cancer progression," Sloan and colleagues concluded in their report.

Previous research had found that caveolin-1 plays a big part in the development of breast cancer tumors, according to a news release from the journal.

More information

The American Cancer Society has more about breast cancer.

SOURCE: American Journal of Pathology, news release, May 22, 2009

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