Breast Cancer Prognosis Winston Salem NC

Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments in Winston Salem.

Allen Russell Chauvenet, MD
(336) 716-4085
Medical Center Blvd,
Winston Salem, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Univ Of Fl Coll Of Med, Gainesville Fl 32610
Graduation Year: 1978

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Miles Robert Cooper, MD
(336) 777-3051
Medicine Center Boulevard,
Winston Salem, NC
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Oncology (Cancer)
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Male
Education
Medical School: Bowman Gray Sch Of Med Of Wake Forest Univ, Winston-Salem Nc 27157
Graduation Year: 1962

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DeNise A LeVitan
(336) 716-2255
Medical Center Blvd
Winston Salem, NC
Specialty
Medical Oncology

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Judith O Hopkins
(336) 277-8800
1010 Bethesda Ct
Winston Salem, NC
Specialty
Hematology / Oncology

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Samer Ernest Bibawi, MD
(336) 277-8800
1010 Bethesda Ct
Winston Salem, NC
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Oncology (Cancer)
Gender
Male
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Medical School: Univ Of Cairo, Fac Of Med, Cairo, Egypt (330-02 Prior 1/71)
Graduation Year: 1988

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Yi-Kong Keung
(336) 716-2255
Medical Center Blvd
Winston Salem, NC
Specialty
Medical Oncology

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Bayard Lowery Powell
(336) 716-2255
Medical Center Blvd
Winston Salem, NC
Specialty
Medical Oncology

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Patricia Joan Zekan, MD
(336) 748-8626
359 Buckingham Rd
Winston Salem, NC
Specialties
Internal Medicine, Medical Oncology
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Female
Education
Medical School: Wv Univ Sch Of Med, Morgantown Wv 26506
Graduation Year: 1978

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Yi-Kong Keung, MD
(336) 716-5847
Dept Of Internal Medicine
Winston Salem, NC
Specialties
Oncology (Cancer)
Gender
Male
Education
Medical School: Univ Of Hong Kong, Fac Of Med, Hong Kong
Graduation Year: 1985

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Hernan Sabio
(336) 716-2255
Medical Center Blvd
Winston Salem, NC
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Hematology / Oncology, Pediatric Hematology-Oncology

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Breast Cancer Prognosis

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FRIDAY, May 22 (HealthDay News) -- Two new studies have found that levels of the protein caveolin-1 found in stromal connective tissue near a breast cancer tumor can accurately predict a patient's prognosis and may provide a pathway to future treatments.

Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K. Witkiewicz, from Thomas Jefferson University in Philadelphia, and colleagues. The findings are published in the June issue of the American Journal of Pathology.

The second study, in the same issue of the journal, found that a similar lack of stromal caveolin-1 in mice was associated with more aggressive tumor growth in the rodents, according to Erica K. Sloan, from the Peter MacCallum Cancer Centre in East Melbourne, Australia, and colleagues.

The findings led Sloan's research team to hypothesize that caveolin-1 may work as a tumor suppressant, at least in stromal tissue.

"These studies suggest that stromal caveolin-1 expression may be a potential therapeutic target and a valuable prognostic indicator of breast cancer progression," Sloan and colleagues concluded in their report.

Previous research had found that caveolin-1 plays a big part in the development of breast cancer tumors, according to a news release from the journal.

More information

The American Cancer Society has more about breast cancer.

SOURCE: American Journal of Pathology, news release, May 22, 2009

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