» » »

Cancer Drug for Alzheimer's Treatment Durham NC

New research suggests that a cancer drug might be able to restore day-to-day memory in patients with Alzheimer's disease. The disease, the most common form of dementia among the elderly, is expected to afflict 120 million people worldwide by 2050. Often the first sign is loss of short-term memory.

Peter Michael Grossi, MD
(919) 684-3271
Box 3807/Neurosurgery,
Durham, NC
Specialties
Neurological Surgery
Gender
Male
Education
Graduation Year: 2002

Data Provided by:
Lyman William Whitlatch, MD
(919) 684-3271
Box 3807,
Durham, NC
Specialties
Neurological Surgery
Gender
Male
Education
Medical School: Boston Univ Sch Of Med, Boston Ma 02118
Graduation Year: 2003

Data Provided by:
Vani Chilukuri
(919) 620-4467
Duke University Medical Ctr
Durham, NC
Specialty
Neurology

Data Provided by:
Timothy Collins
(919) 620-4467
Duke University Medical Ctr
Durham, NC
Specialty
Neurology

Data Provided by:
Larry Bruce Goldstein, MD
(919) 684-3801
Duke Univ Med Ctr
Durham, NC
Specialties
Neurology
Gender
Male
Education
Medical School: Mt Sinai Sch Of Med Of The City Univ Of Ny, New York Ny 10029
Graduation Year: 1981

Data Provided by:
Timothy Merrill George, MD
(919) 684-5013
Box 3272/Neurosurgery,
Durham, NC
Specialties
Neurological Surgery
Gender
Male
Education
Medical School: New York Univ Sch Of Med, New York Ny 10016
Graduation Year: 1986

Data Provided by:
John W Gibbs III, MD
(919) 684-8111
Box 2905 Duke Univ Med Ctr
Durham, NC
Specialties
Neurology
Gender
Male
Education
Medical School: Va Commonwealth Univ, Med Coll Of Va Sch Of Med, Richmond Va 23298
Graduation Year: 1998

Data Provided by:
Michael Jozef Alexander, MD
(919) 668-0650
4523 Busse Bldg Duke South Box 3807,
Durham, NC
Specialties
Neurological Surgery
Gender
Male
Education
Medical School: Georgetown Univ Sch Of Med, Washington Dc 20007
Graduation Year: 1991

Data Provided by:
Kevan E Van Landingham, MD
(919) 684-3532
Dumc 3678 202F Bell Bldg
Durham, NC
Specialties
Neurology
Gender
Male
Education
Medical School: Univ Of Va Sch Of Med, Charlottesville Va 22908
Graduation Year: 1985

Data Provided by:
John Sampson
(919) 620-4467
2100 Erwin Rd
Durham, NC
Specialty
Neurosurgery

Data Provided by:
Data Provided by:

Cancer Drug for Alzheimer's Treatment

Provided By:

TUESDAY, Sept. 8 (HealthDay News) -- New research suggests that a cancer drug might be able to restore day-to-day memory in patients with Alzheimer's disease.

The disease, the most common form of dementia among the elderly, is expected to afflict 120 million people worldwide by 2050. Often the first sign is loss of short-term memory.

"People often joke that they must have Alzheimer's because they can't remember where they put their keys, but for a person with the disease, this type of short-term memory loss is extremely debilitating," study author Ottavio Arancio, an associate professor of pathology and cell biology at Columbia University Medical Center, said in a news release.

The researchers examined a cancer drug from a family of compounds called HDAC inhibitors. The drug tinkers with DNA, and in the mice the researchers studied it appeared to make it easier for neurons in the brain to manufacture new proteins.

That process is critical in the process of recording new memories.

"Because this type of drug has already been approved for some cancer patients, we hope that clinical trials for Alzheimer's disease can start in about three to four years," said co-author Mauro Fa, an associate research scientist at Columbia.

The findings appear in the September issue of the Journal of Alzheimer's Disease.

More information

Learn more about memory from McGill University.

SOURCE: Columbia University, news release, Sept. 3, 2009

Copyright © 2009 ScoutNews, LLC. All rights reserved.

Read Article at HealthDay.com