Chasteberry for Severe PMS Fayetteville NC

Read more about Chasteberry Proves Useful for Moderate to Severe PMS.

Edgar C Garber, MD FACS
1810 Lakeshore Dr
Fayetteville, NC
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Medical School: Med Coll Virginia
Graduation Year: 1944

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Paul Anthony Vieta, MD
(910) 485-1191
911 Hay St
Fayetteville, NC
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Medical School: Umdnj-New Jersey Med Sch, Newark Nj 07103
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Hospital: Cape Fear Valley Med Center, Fayetteville, Nc; Highsmith-Rainey Memorial Hosp, Fayetteville, Nc
Group Practice: Highland Ob-Gyn Clinic

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David Alan Schutzer, MD
(910) 485-1191
911 Hay St
Fayetteville, NC
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Medical School: Umdnj-Robt W Johnson Med Sch, New Brunswick Nj 08901
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Hospital: Cape Fear Valley Med Center, Fayetteville, Nc
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Robert H Morrison, MD FACS
331 Fairfield Rd
Fayetteville, NC
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Gerianne C Geszler
(910) 485-0700
200 Forsythe St
Fayetteville, NC
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Dr.Perry Harmon
(910) 483-6677
Highland OB-GYN Clinic PA, 2301 Robeson St
Fayetteville, NC
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David Alan Schutzer
(910) 485-1191
911 Hay St
Fayetteville, NC
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Obstetrics & Gynecology

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Ernesto Jf Graham, MD
(910) 223-7420
2915 Raeford Rd
Fayetteville, NC
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Dr.Gerianne Geszler
(910) 485-0700
200 Forsythe Street
Fayetteville, NC
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Medical School: Duke Univ Sch Of Med
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Gynecologist (OBGYN)
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Lakshmi Gordon, MD
(910) 323-2103
2053 Valleygate Dr
Fayetteville, NC
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Chasteberry for Severe PMS

Chasteberry Proves Useful for Moderate to Severe PMS.
Date: Monday, June 29, 2009
Source: Maturitas
Related Monographs: Premenstrual Syndrome (PMS), Chasteberry
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Premenstrual syndrome (PMS) is a cluster of physical and emotional symptoms associated with the menstrual cycle. Most women experience some degree of PMS at some point in their menstrual history, although symptoms vary significantly from woman to woman. Reproductive hormones and neurotransmitters are thought to play a central role in the etiology of PMS. Five to ten days prior to menses, plasma estrogens rise and progesterone levels decline. These changes are accompanied by an increase in follicle stimulating hormone (FSH) six to nine days prior to menstruation, and peak aldosterone levels two to eight days before menstruation. Prolactin levels are elevated in most PMS patients. There are many theories around what causes these major changes to occur and why they are more dramatic in some women and less dramatic in others. One theory is that the way that the body uses vitamins and minerals may be a factor. Another hypothesis is that there is some deviation in the viscosity or thickness of the blood along with a change in the amount of water within the red blood cells during the menstrual cycle.

The chasteberry tree finds its origins in the Mediterranean. Its fruit is harvested and dried for medicinal purposes. It has a long folk history of use in women's health. Chasteberry (also known as Vitex agnus castus) has been recommended for use in mild to moderate complaints, especially in endometriosis, menopause, and PMS symptoms.

A recent study sought to determine whether chasteberry is a safe and effective treatment for moderate to severe PMS. The double-blind, placebo controlled, parallel group, multi-center clinical trial included 270 women who were randomly assigned to receive chasteberry extract (40 mg) or placebo for up to three menstrual cycles. Of those enrolled in the study, 202 women completed the treatment phase of the trial. The mean total PMS-diary scores decreased from 29.23 at baseline (0 cycle) to 6.41 at the termination (3rd cycle) for the treatment group and from 28.14 at baseline (0 cycle) to 12.64 at the termination (3rd cycle) for the placebo group. The difference between the treatment group and the placebo group was deemed statistically significant. There were no adverse effects reported in either group. These findings suggest that chasteberry extract appears to be a safe, effective and well-tolerated treatment for women suffering from moderate to severe PMS.1 

1 He Z, Chen R, Zhou Y, et al. Treatment for premenstrual syndrome with Vitex agnus castus: A prospective, randomized, multi-center placebo controlled study in China. Maturitas. 2009;63(1):99-103.

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