Chasteberry for Severe PMS Greensboro NC

Read more about Chasteberry Proves Useful for Moderate to Severe PMS.

Eugene F Russell III, MD
(336) 854-8800
510 N Elam Ave Ste 101
Greensboro, NC
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Obstetrics & Gynecology
Gender
Male
Education
Medical School: Univ Of Va Sch Of Med, Charlottesville Va 22908
Graduation Year: 1965

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Clarence L Wilson II, MD
(910) 763-9833
1200 N Elm St # 1113
Greensboro, NC
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: Univ Of Louisville Sch Of Med, Louisville Ky 40202
Graduation Year: 1974
Hospital
Hospital: New Hanover Reg Med Ctr, Wilmington, Nc; Cape Fear Mem Hosp, Wilmington, Nc
Group Practice: Glen Meade Obstetrics & Gynecology Pa

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Eugene F Russell, MD
(336) 854-8800
510 N Elam Ave
Greensboro, NC
Specialties
Obstetrics & Gynecology
Gender
Male
Education
Medical School: Univ Of Va Sch Of Med, Charlottesville Va 22908
Graduation Year: 1965

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Tara J Cole
(336) 268-3380
301 E Wendover Ave
Greensboro, NC
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Obstetrics & Gynecology

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Lowell Carroll Shinn, MD
(336) 420-3063
501 N Elam Ave
Greensboro, NC
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Obstetrics & Gynecology
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Male
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Medical School: Marshall Univ Sch Of Med, Huntington Wv 25755
Graduation Year: 1985

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Diana Burke Collins, MD
(336) 268-3380
301 E Wendover Ave Ste 300
Greensboro, NC
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Obstetrics & Gynecology
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Female
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Medical School: Bowman Gray Sch Of Med Of Wake Forest Univ, Winston-Salem Nc 27157
Graduation Year: 1987

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Leigh H Jones, MD
(336) 273-2835
301 E Wendover Ave Ste 400
Greensboro, NC
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Obstetrics & Gynecology
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Female
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Medical School: Univ Of Nc At Chapel Hill Sch Of Med, Chapel Hill Nc 27599
Graduation Year: 1990

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Kathy Wray Richardson
(336) 854-8800
510 N Elam Ave Ste 101
Greensboro, NC
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Todd Douglas Meisinger, MD
(336) 854-8800
510 N Elam Ave
Greensboro, NC
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Obstetrics & Gynecology
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Male
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Medical School: St Louis Univ Sch Of Med, St Louis Mo 63104
Graduation Year: 1993
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Hospital: Moses H Cone Memorial Hospital, Greensboro, Nc; Womens Hospital, Greensboro, Nc
Group Practice: Greensboro Ob Gyn Assoc

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Philip David Rose, MD
(336) 832-6873
1200 N Elm St
Greensboro, NC
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Medical School: Univ De Lausanne, Fac De Med, Lausanne, Switzerland
Graduation Year: 1964

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Chasteberry for Severe PMS

Chasteberry Proves Useful for Moderate to Severe PMS.
Date: Monday, June 29, 2009
Source: Maturitas
Related Monographs: Premenstrual Syndrome (PMS), Chasteberry
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Premenstrual syndrome (PMS) is a cluster of physical and emotional symptoms associated with the menstrual cycle. Most women experience some degree of PMS at some point in their menstrual history, although symptoms vary significantly from woman to woman. Reproductive hormones and neurotransmitters are thought to play a central role in the etiology of PMS. Five to ten days prior to menses, plasma estrogens rise and progesterone levels decline. These changes are accompanied by an increase in follicle stimulating hormone (FSH) six to nine days prior to menstruation, and peak aldosterone levels two to eight days before menstruation. Prolactin levels are elevated in most PMS patients. There are many theories around what causes these major changes to occur and why they are more dramatic in some women and less dramatic in others. One theory is that the way that the body uses vitamins and minerals may be a factor. Another hypothesis is that there is some deviation in the viscosity or thickness of the blood along with a change in the amount of water within the red blood cells during the menstrual cycle.

The chasteberry tree finds its origins in the Mediterranean. Its fruit is harvested and dried for medicinal purposes. It has a long folk history of use in women's health. Chasteberry (also known as Vitex agnus castus) has been recommended for use in mild to moderate complaints, especially in endometriosis, menopause, and PMS symptoms.

A recent study sought to determine whether chasteberry is a safe and effective treatment for moderate to severe PMS. The double-blind, placebo controlled, parallel group, multi-center clinical trial included 270 women who were randomly assigned to receive chasteberry extract (40 mg) or placebo for up to three menstrual cycles. Of those enrolled in the study, 202 women completed the treatment phase of the trial. The mean total PMS-diary scores decreased from 29.23 at baseline (0 cycle) to 6.41 at the termination (3rd cycle) for the treatment group and from 28.14 at baseline (0 cycle) to 12.64 at the termination (3rd cycle) for the placebo group. The difference between the treatment group and the placebo group was deemed statistically significant. There were no adverse effects reported in either group. These findings suggest that chasteberry extract appears to be a safe, effective and well-tolerated treatment for women suffering from moderate to severe PMS.1 

1 He Z, Chen R, Zhou Y, et al. Treatment for premenstrual syndrome with Vitex agnus castus: A prospective, randomized, multi-center placebo controlled study in China. Maturitas. 2009;63(1):99-103.

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