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Gum Disease and Heart Disease Cary NC

A genetic link between gum disease (periodontitis) and heart disease has been discovered by German scientists. The association between periodontitis and coronary heart disease (CHD) has been known for years in Cary, but a genetic link between the conditions hadn't been confirmed. The University of Kiel team found that the two diseases share a genetic variant on chromosome 9.

Sidney C Smith Jr., MD
(919) 966-5201
130 Mason Farm Rd
Chapel Hill, NC
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UNC Cardiology
Specialties
Cardiology

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Divyang Rambhai Patel, MD
(919) 419-7410
103 Oxford Creek Rd
Cary, NC
Specialties
Cardiology
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Male
Education
Medical School: Municipal Med Coll, Gujarat Univ, Ahmedabad, Gujarat, India
Graduation Year: 1986

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Bruce Warren Usher
(919) 851-6901
300 Ashville Ave
Cary, NC
Specialty
Cardiology

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Jeffrey Richard Daw, MD
(919) 851-6901
400 Ashville Ave Ste 320
Cary, NC
Specialties
Cardiology
Gender
Male
Education
Medical School: Univ Of Nc At Chapel Hill Sch Of Med, Chapel Hill Nc 27599
Graduation Year: 1990

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Bruce Warren Usher Jr, MD
(919) 851-6901
300 Ashville Ave Ste 301
Cary, NC
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Cardiology
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Male
Education
Medical School: Med Univ Of Sc Coll Of Med, Charleston Sc 29425
Graduation Year: 1993

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Shaoshan Wang, MD
(919) 216-1976
103 Hadley Creek Dr
Cary, NC
Specialties
Cardiology
Gender
Male
Education
Medical School: Shandong Med Univ, Jinan, Shandong, China
Graduation Year: 1992

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Radha Goel Kachhy, MD
(919) 862-5100
103 Brook Fryar St
Cary, NC
Specialties
Cardiology
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Male
Education
Graduation Year: 2007

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Sameh Khamis Mobarek
(919) 851-6901
300 Ashville Ave
Cary, NC
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Cardiology

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Jeffrey Richard Daw
(919) 851-6901
300 Ashville Ave
Cary, NC
Specialty
Cardiology, Internal Medicine

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Sunil J Desai, MD, FACC
(919) 233-0059
300 Keisler Dr Ste 204
Cary, NC
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Cardiology, Internal Medicine
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Male
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Graduation Year: 2007

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Gum Disease and Heart Disease

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TUESDAY, May 26 (HealthDay News) -- A genetic link between gum disease (periodontitis) and heart disease has been discovered by German scientists.

The association between periodontitis and coronary heart disease (CHD) has been known for years, but a genetic link between the conditions hadn't been confirmed. The University of Kiel team found that the two diseases share a genetic variant on chromosome 9.

"We studied a genetic locus on chromosome 9p21.3 that had previously been identified to be associated with myocardial infarction [heart attack], in a group of 151 patients suffering from the most aggressive, early-onset forms of periodontitis, and a group of 1,097 CHD patients who had already had a heart attack. The genetic variation associated with the clinical pictures of both diseases was identical," Dr. Arne Schaefer said in a European Society of Human Genetics (ESHG) news release.

He and his colleagues verified this genetic association in additional groups of 180 periodontitis patients and 1,100 CHD patients.

The study was presented May 25 at the annual ESHG conference, in Vienna, Austria.

Because of the link between periodontitis and CHD, "we think that periodontitis should be taken very seriously by dentists and diagnosed and treated as early as possible," Schaefer said. He noted that periodontitis and CHD share risk factors such as smoking, diabetes and obesity.

"Now that we know for sure that there is a strong genetic link, patients with periodontitis should try to reduce their risk factors and take preventive measures at an early stage," he said. "We hope that our findings will make it easier to diagnose the disease at an early stage, and that in future, a greater insight into the specific pathophysiology might open the way to effective treatment before the disease can take hold."

More information

The American Academy of Periodontology has more about periodontitis.

SOURCE: European Society of Human Genetics, news release, May 25, 2009

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