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Gum Disease and Heart Disease Durham NC

A genetic link between gum disease (periodontitis) and heart disease has been discovered by German scientists. The association between periodontitis and coronary heart disease (CHD) has been known for years in Durham, but a genetic link between the conditions hadn't been confirmed. The University of Kiel team found that the two diseases share a genetic variant on chromosome 9.

Sidney C Smith Jr., MD
(919) 966-5201
130 Mason Farm Rd
Chapel Hill, NC
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UNC Cardiology
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Cardiology

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Fred Ross Cobb, MD
3810 Trent Dr Ste 2f,
Durham, NC
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Cardiology
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Medical School: Univ Of Ms Sch Of Med, Jackson Ms 39216
Graduation Year: 1964

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Richard P Konstance II, MD
(919) 684-2407
Irwin Rd/Duke Hosp N Ste 7624
Durham, NC
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Medical School: Allegheny Univ Of Hlth Sciences, Philadelphia Pa 19129
Graduation Year: 1999

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Ian James Welsby, MD
(919) 668-2699
Durham, NC
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Medical School: Charing Cross And Westminster Med Sch, London (352-07 Pr 01/71)
Graduation Year: 1990

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Kevin L Thomas
(919) 684-8111
2100 Erwin Rd
Durham, NC
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Adrian Felipe Hernandez, MD
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1107 Minerva Ave
Durham, NC
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Cardiology
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Medical School: Univ Of Tx Southwestern Med Ctr At Dallas, Med Sch, Dallas Tx 75235
Graduation Year: 1997

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Michael Characholou, MD
(919) 668-0950
Box 31013 DUMC,
Durham, NC
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Graduation Year: 2007

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Daniel Haithcock, MD
Durham, NC
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Graduation Year: 2007

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Michael Paul Carboni, MD
(919) 681-2916
DUMC Box 3090,
Durham, NC
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Cardiology
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Medical School: Northeastern Oh Univs Coll Of Med, Rootstown Oh 44272
Graduation Year: 1990
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Hospital: St Francis Hosp, Wilmington, De
Group Practice: Nemours Childrens Clinic Wilmington; Nemours Foundation

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Pamela Susan Douglas, MD
(919) 681-2690
Erwin Road ? Duke North 7451 Mailstop 3943 Erwin Rd,
Durham, NC
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Medical School: Va Commonwealth Univ, Med Coll Of Va Sch Of Med, Richmond Va 23298
Graduation Year: 1978

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Gum Disease and Heart Disease

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TUESDAY, May 26 (HealthDay News) -- A genetic link between gum disease (periodontitis) and heart disease has been discovered by German scientists.

The association between periodontitis and coronary heart disease (CHD) has been known for years, but a genetic link between the conditions hadn't been confirmed. The University of Kiel team found that the two diseases share a genetic variant on chromosome 9.

"We studied a genetic locus on chromosome 9p21.3 that had previously been identified to be associated with myocardial infarction [heart attack], in a group of 151 patients suffering from the most aggressive, early-onset forms of periodontitis, and a group of 1,097 CHD patients who had already had a heart attack. The genetic variation associated with the clinical pictures of both diseases was identical," Dr. Arne Schaefer said in a European Society of Human Genetics (ESHG) news release.

He and his colleagues verified this genetic association in additional groups of 180 periodontitis patients and 1,100 CHD patients.

The study was presented May 25 at the annual ESHG conference, in Vienna, Austria.

Because of the link between periodontitis and CHD, "we think that periodontitis should be taken very seriously by dentists and diagnosed and treated as early as possible," Schaefer said. He noted that periodontitis and CHD share risk factors such as smoking, diabetes and obesity.

"Now that we know for sure that there is a strong genetic link, patients with periodontitis should try to reduce their risk factors and take preventive measures at an early stage," he said. "We hope that our findings will make it easier to diagnose the disease at an early stage, and that in future, a greater insight into the specific pathophysiology might open the way to effective treatment before the disease can take hold."

More information

The American Academy of Periodontology has more about periodontitis.

SOURCE: European Society of Human Genetics, news release, May 25, 2009

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